Statistical and game theoretical approach for combining models

• Project/Area Number: 21700316
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Statistical science
• Research Institution: The University of Tokyo (2010); The Institute of Physical and Chemical Research (2009)
• Principal Investigator: SHIRAISHI Yuichi The University of Tokyo, 医科学研究所, 特任研究員 (70516880)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000); Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 統計的学習理論 / スパース正則化学習 / 多値判別 / 遺伝子発現 / 相乗効果 / バイオインフォマティクス / 統計的検定理論 / マルコフ連鎖モンテカルロ / ensemble learning / stacking / groun lasso / gene regulatory network / state space model

Research Abstract

A efficient approach for combining binary classifiers for multi-class classification problems was developed. Then, a new statistical method for inferring network from differently stimulated gene expression data was developed. Finally, a rank-based nonparametric statistical test for measuring the synergistic effects between two gene sets was proposed.

Research Products

• [Journal Article] Statistical approaches for combining binary classifiers for multiclass classification (2011)
  • Author(s): Yuichi Shiraishi, Kenji Fukumizu
  • Journal Title: Neurocomputing 74 Pages: 680-688
  • Peer Reviewed
• [Journal Article] Statistical approaches for combining binary classifiers for multiclass classification (2011)
  • Author(s): Yuichi Shiraishi, Kenji Fukumizu
  • Journal Title: Neurocomputing Volume: 74 Pages: 680-688
  • Peer Reviewed
• [Journal Article] Inferring cluster-based networks from differently stimulated multiple time-course gene expression data (2010)
  • Author(s): Yuichi Shiraishi, Shuhei Kimura, Mariko Okada
  • Journal Title: Bioinformatics 26 Pages: 1073-1081
  • Peer Reviewed
• [Journal Article] Inferring cluster-based networks from differently stimulated multiple time-course gene expression data (2010)
  • Author(s): Yuichi Shiraishi, Shuhei Kimura, Mariko Okada
  • Journal Title: Bioinformatics Volume: 26 Pages: 1073-1081
  • Peer Reviewed
• [Presentation] A rank-based statistical test for measuring synergistic effects between two gene sets (2010)
  • Author(s): 白石友一
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会合同大会
  • Place of Presentation: 神戸
  • Year and Date: 2010-12-10
• [Presentation] Arank-based statistical test for measuring synergistic effects between two gene sets (2010)
  • Author(s): 白石友一
  • Organizer: 第33回日本分子生物学会年会・第83回日本生化学会合同大会
  • Place of Presentation: 神戸・神戸ポートアイランド
  • Year and Date: 2010-12-10
• [Presentation] Predicting regulatory networks from large scale time-course microarray data under several stimulation conditions on MCF-7 cells (2010)
  • Author(s): Yuichi Shiraishi
  • Organizer: 9th European Conference on Computational Biology
  • Place of Presentation: Ghent, Belgium.
  • Year and Date: 2010-09-27
• [Presentation] Predicting regulatory networks from large scale time-course microarray data under several stimulation conditions on MCF-7 cells (2010)
  • Author(s): 白石友一
  • Organizer: 9th European Conference on Computational Biology
  • Place of Presentation: Ghent, Belgium
  • Year and Date: 2010-09-27
• [Presentation] Statistical approaches for combining binary classifiers for multiclass classification (2009)
  • Author(s): 白石友一
  • Organizer: 2009年度統計関連学会連合大会
  • Place of Presentation: 京都
  • Year and Date: 2009-09-08
• [Presentation] Inferring cluster-based networks from differently stimulated multiple time-course gene expression data (2009)
  • Author(s): 白石友一
  • Organizer: 2009年度統計関連学会連合大会
  • Place of Presentation: 京都
  • Year and Date: 2009-09-07
• [Presentation] Inferring cluster-based networks from differently stimulated multiple time-course gene expression data (2009)
  • Author(s): Yuichi Shiraishi
  • Organizer: 17th Annual International conference on Intelligent Systems for Molecular Biology
  • Place of Presentation: Stockholm, Sweden.
  • Year and Date: 2009-06-29
• [Presentation] Inferring cluster-based networks from differently stimulated multiple time-course gene expression data (2009)
  • Author(s): 白石友一
  • Organizer: 17th Annual International conference on Intelligent Systems for Molecular Biology
  • Place of Presentation: Stockholm, Sweden
  • Year and Date: 2009-06-29