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Estimation of structural characteristics of synaptic networks based on the functional networks derived from neural activity

Research Project

Project/Area Number 21700334
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Bioinformatics/Life informatics
Research InstitutionRitsumeikan University

Principal Investigator

KITANO Katsunori  Ritsumeikan University, 情報理工学部, 准教授 (90368001)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords神経回路 / 数理モデル / シミュレーション / 同期
Research Abstract

We explored the possibility to extract structural characteristics of a synaptic network from neuronal spiking activity analyzing similarity between the synaptic network and the functional network generated by pairwise spike correlation. We developed the method to construct a functional network based on pairwise spike correlation and a condition about the number of functional connections per a neuron. Our result indicated that the proposed method could yield the functional networks that showed similar structural characteristics to synaptic networks with respect to statistics characterizing network structure such as clustering coefficients and average shortest path length.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (4 results)

All 2009 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (2 results) Remarks (1 results)

  • [Journal Article] Functional networks based on pairwise spike synchrony can capture topologies of synaptic connectivity in a local cortical network model2009

    • Author(s)
      Katsunori Kitano、Kazuhiro Yamada
    • Journal Title

      Lecture Notes in Computer Science 5506巻

      Pages: 978-985

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Presentation] 局所大脳皮質神経回路活動から構成された機能的神経回路の特性2009

    • Author(s)
      吉田裕宣、北野勝則
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2009-09-16
    • Related Report
      2010 Final Research Report
  • [Presentation] 局所大脳皮質神経活動から構成された機能的神経回路の特性2009

    • Author(s)
      吉田裕宣、北野勝則
    • Organizer
      第32回神経科学大会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2009-09-16
    • Related Report
      2009 Annual Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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