| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Research Abstract |
In this study, we developed a computational model of human gait based on the cortico-basal ganglia loop circuit. The model reproduced gait patterns of normal subjects and patients with Parkinson' s disease(PD). First, we calculated quantitative indices on gait patterns, and characterized the differences between young healthy subjects and elderly healthy subjects and between elderly healthy subjects and elderly PD patients. Second, we constructed the computational model consisting of the cortico-basal ganglia loop and neuronal oscillators. The computer simulation using this model reproduced the gait motion of the legs of elderly healthy subjects and elderly PD patients, respectively. We confirmed that the cortico-basal ganglia loop could change the gait control.
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