Development of new model to examine LTM formation in vitro
| Project/Area Number |
21700376
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Neuroscience in general
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| Research Institution | 財団法人東京都医学研究機構 (2010)
Tokyo Metropolitan Organization for Medical Research (2009) |
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Principal Investigator |
UENO Kohei 財団法人東京都医学研究機構, 東京都神経科学総合研究所, 研究員 (40332556)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 分子 / 細胞神経科学 / ショウジョウバエ / イメージング / 学習記憶 / 可塑性 / ショウジョウバェ |
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| Research Abstract |
The physiological mechanisms of memory formation and storage is still unclear. In this report, I tried to examine the mechanisms by using isolated brain of Drosophila melanogaster. I found that the fly brain expressing fluorescent probe to monitor neural activity responded by electrical stimulation. Finally, I found that the electrical stimulation successfully induced the neural plasticity associate odor-avoidance memory in fly. By some experiments, I propose the new neural model to explain the odor-avoidance memory.
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Report
(3 results)
Research Products
(10 results)
