The analysis of Reelin-Dab1 signaling pathway for dendrite formation and guidance
| Project/Area Number |
21700383
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | Keio University |
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Principal Investigator |
HONDA Takao 慶應義塾大学, 医学部, 助教 (30365225)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 神経発生 / 分化 / 異常 / reelin / dab1 / reeler / yotari / 樹状突起 |
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| Research Abstract |
As we found that Dab1 is involved in dendrite formation and can translocate into nucleus, we hypothesized that Reelin regulates an expression of dendrite formation related genes through the Dab1 nuclear translocation. When we coexpressed dab1 knockdown ve
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Report
(2 results)
Research Products
(9 results)
