| Project/Area Number |
21700389
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
KAJIWARA Riichi National Institute of Advanced Industrial Science and Technology, バイオメディカル研究部門, 主任研究員 (60356772)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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| Keywords | 神経回路網 / 神経活動イメージング / 扁桃体 / 嗅内皮質 / 梨状皮質 / 嗅覚 / モルモット / 単離脳標本 / 膜電位感受性色素 / 光計測 |
|---|
| Research Abstract |
In order to reveal the functional organization of the amygdaloid network, we developed the optical recording system using a guinea pig isolated whole brain. By using this experimental setup, we analyzed the dependency of stimulus intensity and frequency on the spatiotemporal patterns of the neural activity evoked by the electrical shock to olfactory nerve. In addition to the imaging study, laminar profiles of evoked field potentials were recorded in the amygdala using a multichannel silicon probe. Current source density analysis performed on the field responses revealed the propagation pattern of the neural activity in the deep structure of the amygdaloid cortex.
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