Chromatin Dynamics during Neuronal Differentiation
Project/Area Number |
21700404
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Neurochemistry/Neuropharmacology
|
Research Institution | Osaka University |
Principal Investigator |
SUGO Noriyuki Osaka University, 大学院・生命機能研究科, 助教 (20372625)
|
Project Period (FY) |
2009 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
Keywords | 発生・分化・老化 / 遺伝子発現調節 / クロマチン / DNA修復 / 分子・細胞神経科学 / 発生・分化 / 大脳皮質 / ゲノム |
Research Abstract |
Molecular mechanism of neuronal differentiation including transcription and chromatin regulation has remained unclear. In this study, we revealed that that histone deacetylase (HDAC) and DNA repair protein play a critical role in cortical differentiation.
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Report
(3 results)
Research Products
(11 results)