Analysis of the reactivation of food-odor evoked activity in the olfactory cortex
Project/Area Number |
21700429
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Neurophysiology and muscle physiology
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Research Institution | The University of Tokyo |
Principal Investigator |
MANABE Hiroyuki The University of Tokyo, 大学院・医学系研究科, 特任研究員 (80511386)
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Project Period (FY) |
2009 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | 神経科学 / 嗅覚 / 電気生理 / 睡眠 / 嗅皮質 / 鋭波 / sharp wave |
Research Abstract |
The olfactory cortex is functionally isolated from the external odor world during slow-wave sleep. However, the neuronal activity pattern in the olfactory cortex and its functional role during slow-wave sleep were not well understood. Here, I demonstrated in freely behaving rats that the anterior piriform cortex repeatedly generated sharp waves accompanied by synchronized discharges of numerous cortical neurons during slow-wave sleep. The olfactory cortex sharp waves drove synchronized top-down inputs to the olfactory bulb. The olfactory cortex sharp waves may represent the reactivation of the neuronal activation pattern during preceding waking period and contribute to the memory consolidation process in the olfactory cortex.
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Report
(3 results)
Research Products
(7 results)