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Spinal and cortical contribution to control of primate grasping

Research Project

Project/Area Number 21700437
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Neurophysiology and muscle physiology
Research InstitutionNational Center of Neurology and Psychiatry

Principal Investigator

TAKEI Tomohiko  独立行政法人国立精神・神経医療研究センター, 神経研究所・霊長類管理室, 任期付研究員 (50527950)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords把握運動 / 運動制御 / 脊髄 / 一次運動野 / 霊長類
Research Abstract

Grasping is a highly complex movement, which is involved by 27 hand and arm muscles. Here we explored how the spinal premotor interneurons (PreM-INs) in primate cervical cord and corcicomotoneuronal cells (CM-cells) in primary motor cortex are involved in coordination of the hand muscles. Our results revealed that the PreM-INs had divergent output effects on hand muscles to form the muscle synergy, which is coordinated muscle activities, and the diversity was broader than the CM-cells did. This result suggested that the spinal interneurons play an important role for a coordination of hand muscles during a primate grasping.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (12 results)

All 2010 2009 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (9 results) Remarks (1 results)

  • [Journal Article] Spinal interneurons facilitate coactivation of hand muscles during a precision grip task in monkeys2010

    • Author(s)
      Tomohiko Takei, Kazuhiko Seki
    • Journal Title

      The Journal of Neuroscience 30(50)

      Pages: 17041-17050

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Spinal interneurons facilitate coactivation of hand muscles during a precision grip task in monkeys2010

    • Author(s)
      Tomohiko Takei, Kazuhiko Seki
    • Journal Title

      The Journal of Neusoscience

      Volume: 30(50) Pages: 17041-17050

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 脊髄介在ニューロンは把握運動におけるシナジーの形成に貢献しているか?2010

    • Author(s)
      武井智彦、関和彦
    • Organizer
      第4回MotorControl研究会
    • Place of Presentation
      岡崎カンファレンスセンター(岡崎・愛知)
    • Year and Date
      2010-05-29
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Postspike effects of spinal interneurons on hand muscles in monkeys performing a precision grip.2009

    • Author(s)
      Tomohiko Takei, Kazuhiko seki
    • Organizer
      第39回北米神経科学学
    • Place of Presentation
      マコーミックプレイス(シカゴ・米国)
    • Year and Date
      2009-10-19
    • Related Report
      2010 Final Research Report
  • [Presentation] Post-spike effects of spinal interneurons on hand muscles in monkeys performing a precision grip.2009

    • Author(s)
      武井智彦、関和彦
    • Organizer
      第39回北米神経科学学会
    • Place of Presentation
      マコーミックプレィス(シカゴ・米国)
    • Year and Date
      2009-10-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] Postspike effects of spinal interneurons on hand muscles in monkeys performing a precision grip task.2009

    • Author(s)
      Tomohiko Takei, Kazuhiko seki
    • Organizer
      第32回日本神経科学学会
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2009-09-18
    • Related Report
      2010 Final Research Report
  • [Presentation] Post-spike effects of spinal interneurons on hand muscles in monkeys performing a precision grip task.2009

    • Author(s)
      武井智彦、関和彦
    • Organizer
      第32回日本神経科学学会
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2009-09-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] Spinomuscular coherence in monkey : taskdependent modulation and comparison with corticomuscular coherence.2009

    • Author(s)
      武井智彦、関和彦
    • Organizer
      第36回国際生理学会
    • Place of Presentation
      京都国際会議場(京都)
    • Year and Date
      2009-07-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] 把握運動の制御における脊髄・大脳皮質神経機構の役割2009

    • Author(s)
      武井智彦、関和彦
    • Organizer
      第3回MotorControl研究会
    • Place of Presentation
      岡崎カンファレンスセンター(岡崎・愛知)
    • Year and Date
      2009-05-30
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] Contrasting roles of spinal and cortical neurons in the control of grasping.2009

    • Author(s)
      Tomohiko Takei, Kazuhiko Seki
    • Organizer
      第19回Meeting of The Society for the Neural Control of Movement
    • Place of Presentation
      The WaikoloaBeach Marriott Resort(ハワイ・米国)
    • Year and Date
      2009-04-29
    • Related Report
      2010 Final Research Report
  • [Presentation] Contrasting roles of spinal and cortical neurons in the control of grasping.2009

    • Author(s)
      武井智彦、関和彦
    • Organizer
      第19回Meeting of The Society for the Neural Control of Movement
    • Place of Presentation
      The Waikoloa Beach Marriott Resort(ハワイ・米国)
    • Year and Date
      2009-04-29
    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.ncnp.go.jp/pdf/news_101216.pdf

    • Related Report
      2010 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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