| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Research Abstract |
To identify modifier genes for type 1 diabetes in the Komeda diabetes-prone (KDP) rat, we performed genetic analysis using progeny produced from two different crosses. Genetic analysis of these two crosses revealed that modifier genes are located on several chromosomal regions, and that some of them showed age-or sex-specific effects. A whole picture of the genetic loci for type 1 diabetes in the KDP rat was clarified.
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