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Advanced method of bioimaging using fluorescent organic nanocrystals

Research Project

Project/Area Number 21700456
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Biomedical engineering/Biological material science
Research InstitutionOsaka University (2010)
Tohoku University (2009)

Principal Investigator

BABA Koichi  Osaka University, 医学系研究科, 特任講師(常勤) (00436172)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywordsバイオイメージング / 蛍光性有機ナノ結晶 / 共焦点レーザー顕微鏡観察 / 培養細胞イメージング / 有機溶媒フリー / 界面活性剤フリー / 再沈法
Research Abstract

Since a fluorescence microscopy observation is a useful technique for investigating cells and tissues conditions, this observation techniques are widely used. Recently, the development of the novel type of fluorescence microscopy observation techniques have been strongly desired along with the needs of medical doctors and patients against medical treatment and their related science technologies. In this research, novel type of fluorescence microscopy observation using fluorescent organic nanocrystals was successfully demonstrated for the first time, which will be useful for beneficial future research developments in this field.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (12 results)

All 2011 2010 2009

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (6 results) Book (2 results)

  • [Journal Article] Poly(N-isopropylacrylamide)-Based Thermoresponsive Behavior of Fluorescent Organic Nanocrystals2011

    • Author(s)
      Koichi Baba, Hitoshi Kasai, Kohji Nishida, Hachiro Nakanishi
    • Journal Title

      Japanese Journal of Applied Physics Vol.50

    • NAID

      40017446816

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Poly(N-isopropylacrylamide)-Based Thermoresponsive Behavior of Fluorescent Organic Nanocrystals2011

    • Author(s)
      Koichi Baba, et al
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: VOL.50

    • NAID

      40017446816

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Organic Solvent-Free Fluorescence Confocal Imaging of Living Cells Using Pure Nanocrystal Forms of Fluorescent Dyes2009

    • Author(s)
      Koichi Baba, Hitoshi Kasai, Akito Masuhara, Hidetoshi Oikawa, Hachiro Nakanishi
    • Journal Title

      Japanese Journal of Applied Physics Vol.48

    • NAID

      40016844246

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Organic Solvent-Free Fluorescence Confocal Imaging of Living Cells Using Pure Nanocrystal Forms of Fluorescent Dves2009

    • Author(s)
      Koichi Baba, et al
    • Journal Title

      Japanese Journal of Applied Physics 48

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Organic Nanocrystals for Biomedical Applications2010

    • Author(s)
      Koichi Baba
    • Organizer
      Functionalized Nanobiomaterials for Medical Applications, Materials Research Society, USA (国際学会)
    • Place of Presentation
      Denver Marriott Tech Center, Denver, Colorado, USA
    • Year and Date
      2010-10-05
    • Related Report
      2010 Final Research Report
  • [Presentation] Organic Nanocrystals for Biomedical Applications2010

    • Author(s)
      Koichi Baba, et al
    • Organizer
      Functionalized Nanobiomaterials for MedicalApplications, Materials Research Society, USA(国際学会)
    • Place of Presentation
      Denver Marriott Tech Center, Denver, Colorado, USA
    • Year and Date
      2010-10-05
    • Related Report
      2010 Annual Research Report
  • [Presentation] Fluorescent Organic Nanocrystals for Bioimaging2010

    • Author(s)
      Koichi Baba
    • Organizer
      XIX IntenationalMaterials Research Congress (国際学会)
    • Place of Presentation
      Cancun, Mexico
    • Year and Date
      2010-08-16
    • Related Report
      2010 Final Research Report
  • [Presentation] Fluorescent Organic Nanocrystals for Bioimaging2010

    • Author(s)
      Koichi Baba, et al
    • Organizer
      XIX IntenationalMaterials Research Congress
    • Place of Presentation
      Cancun, Mexico
    • Year and Date
      2010-08-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] 有機ナノ結晶を用いる癌の光線力学療法およびバイオイメージング2009

    • Author(s)
      馬場耕一
    • Organizer
      第9回東北大学多元物質科学研究所研究発表会
    • Place of Presentation
      仙台
    • Year and Date
      2009-12-10
    • Related Report
      2010 Final Research Report
  • [Presentation] 有機ナノ結晶を用いる癌の光線力学療法およびバイオイメージング2009

    • Author(s)
      馬場耕一, 他
    • Organizer
      第9画東北大学多元物質科学研究所研究表会
    • Place of Presentation
      仙台
    • Year and Date
      2009-12-10
    • Related Report
      2009 Annual Research Report
  • [Book] Organic Nanocrystals for Nanomedicine and Biophotonics in Nanocrystals2010

    • Author(s)
      Koichi Baba, Hitoshi Kasai, Kohji Nishida, Hachiro Nakanishi
    • Publisher
      Sciyo, Croatia
    • Related Report
      2010 Final Research Report
  • [Book] Organic Nanocrystals for Nanomedicine and Biophotonics2010

    • Author(s)
      Koichi Baba, et al
    • Publisher
      Sciyo, Croatia
    • Related Report
      2010 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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