Development of 3D-fibrous scaffolds with ability of stimulating mesenchymal stem cells
| Project/Area Number |
21700487
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Nagoya Institute of Technology |
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Principal Investigator |
AKIKO Obata 名古屋工業大学, 大学院・工学研究科, 助教 (40402656)
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| Research Collaborator |
NAKAMURA Jin 名古屋工業大学, 大学院・工学研究科, 博士後期課程二年
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 生体材料 / 組織工学 / ハイブリッド材料 / 細胞培養 / 立体型不織布 / 骨再建用スキャホールド材料 / エレクトロスピニング / シリコン種イオン |
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| Research Abstract |
Novel fibrous materials with three dimensional structure were developed for use in the tissue engineering field. Ceramic particles releasing silicate ions, which have been reported to stimulate cell functions, were combined with biodegradable polymer to prepare fibrous materials enhancing cell proliferation and mineralization. The prepared fibrous materials showed flexibility and elasticity. Results of cell culture tests for the materials showed osteoblast-like cells proliferated inside of the fibrous structure of the materials.
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Report
(4 results)
Research Products
(109 results)
