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Analysis of autonomic nerve by chromogranin A during locomotor respiratory coupling

Research Project

Project/Area Number 21700547
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Rehabilitation science/Welfare engineering
Research InstitutionNihon institute of Medical Science

Principal Investigator

KERA Takeshi  Nihon institute of Medical Science, 保健医療学部・リハビリテーション学科, 准教授 (50449435)

Co-Investigator(Renkei-kenkyūsha) TAMAKI Akira  兵庫医療大学, リハビリテーション学部, 教授 (70269851)
Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords運動呼吸同調現象 / 唾液クロモグラニンA / 呼吸困難感 / クロモグラニンA / 呼吸筋酸素摂取量
Research Abstract

We studied the effect of cycle ergometer pedal ratio calculated during locomotor respiratory coupling (LRC) on ventilatory indicators and salivary chromogranin A. Twenty-five subjects participated in our study. These subjects were divided into 2 groups. One group performed pedaling at a rate of 50 rotations per minute (rpm), and the other group performed pedaling at 40 rpm. First, the subjects pedaled at anaerobic threshold(AT) under the spontaneous breathing condition for 10 min, and then performed the same exercise under LRC. The 50-rpm group showed persistent dyspnea under LRC; however, the 40-rpm group showed a significant decrease in the respiratory rate and dyspnea.Human salivary chromogranin A level was not related to coupling between pedaling and respiration. Dyspnea decreased when the breathing rate during spontaneous breathing was lesser than that during LRC, but did not decrease when the former was greater than the latter. Nonetheless, we could not clarify the benefit of LRC on ventilatory indicators and human salivary chromogranin A.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (5 results)

All 2011 2010

All Journal Article (3 results) (of which Peer Reviewed: 2 results) Presentation (2 results)

  • [Journal Article] ペダル回転数が運動呼吸同調現象誘導時の換気諸量と唾液クロモグラニンAの分泌に与える影響2011

    • Author(s)
      解良武士, 大島洋平, 玉木彰
    • Journal Title

      理学療法科学 26巻(印刷中)

    • NAID

      10029619177

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] ペダル回転数が運動呼吸同調現象誘導時の換気諸量と唾液クロモグラニンAの分泌に与える影響2011

    • Author(s)
      解良武士, 大島洋平, 玉木彰
    • Journal Title

      理学療法科学

      Volume: 26(未定)

    • NAID

      10029619177

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 呼吸困難感の感知モデルからみた呼吸リハビリテーションアプローチ2010

    • Author(s)
      解良武士, 藍原章子, 一場友実
    • Journal Title

      理学療法-臨床,研究,教育- 17巻

      Pages: 9-14

    • NAID

      130004949079

    • Related Report
      2010 Final Research Report
  • [Presentation] 運動呼吸同調現象の誘発が呼吸様式へ及ぼす影響2011

    • Author(s)
      解良武士, 玉木彰, 大島洋平, 松下哲也
    • Organizer
      第46回 日本理学療法学術大会
    • Place of Presentation
      宮崎県
    • Year and Date
      2011-05-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] 運動呼吸同調現象の誘発が呼吸様式へ及ぼす影響2011

    • Author(s)
      解良武士, 玉木彰, 大島洋平, 松下哲也
    • Organizer
      第46回日本理学療法学術大会
    • Place of Presentation
      宮崎
    • Related Report
      2010 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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