Analysis of autonomic nerve by chromogranin A during locomotor respiratory coupling
| Project/Area Number |
21700547
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Nihon institute of Medical Science |
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Principal Investigator |
KERA Takeshi Nihon institute of Medical Science, 保健医療学部・リハビリテーション学科, 准教授 (50449435)
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| Co-Investigator(Renkei-kenkyūsha) |
TAMAKI Akira 兵庫医療大学, リハビリテーション学部, 教授 (70269851)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 運動呼吸同調現象 / 唾液クロモグラニンA / 呼吸困難感 / クロモグラニンA / 呼吸筋酸素摂取量 |
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| Research Abstract |
We studied the effect of cycle ergometer pedal ratio calculated during locomotor respiratory coupling (LRC) on ventilatory indicators and salivary chromogranin A. Twenty-five subjects participated in our study. These subjects were divided into 2 groups. One group performed pedaling at a rate of 50 rotations per minute (rpm), and the other group performed pedaling at 40 rpm. First, the subjects pedaled at anaerobic threshold(AT) under the spontaneous breathing condition for 10 min, and then performed the same exercise under LRC. The 50-rpm group showed persistent dyspnea under LRC; however, the 40-rpm group showed a significant decrease in the respiratory rate and dyspnea.Human salivary chromogranin A level was not related to coupling between pedaling and respiration. Dyspnea decreased when the breathing rate during spontaneous breathing was lesser than that during LRC, but did not decrease when the former was greater than the latter. Nonetheless, we could not clarify the benefit of LRC on ventilatory indicators and human salivary chromogranin A.
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Report
(3 results)
Research Products
(5 results)
