Detection of the brain areas involved in the uni- and bi-manual motor learning

• Project/Area Number: 21700551
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Jobu University
• Principal Investigator: SEKIGUCHI Hirofumi Jobu University, ビジネス情報学部, 准教授 (20392201)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2009: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
• Keywords: 神経科学 / 脳・神経 / fMRI / 運動学習 / 力 / 経頭蓋磁気刺激

Research Abstract

The learning effect of a unimanual motor task (a grip force modulation) remained after a bimanual motor task, whereas that of a bimanual motor task disappeared after a unimanual motor task. These results were not consistent with that of a previous study by Nozaki et al.(2006). Current results suggest that the neural mechanism related to motor learning is different between hand and arm. The fMRI study suggested that the learning effect of a unimanual task was stored at the primary motor area.

Research Products

• [Journal Article] Contraction history produces task-specific variations in spinal excitability in healthy human soleus muscle (2011)
  • Author(s): Uematsu, A., Sekiguchi, H., Kobayashi, H., Hortobagyi, T., Suzuki, S.
  • Journal Title: Muscle & Nerve 43[Accepted in Dec 7] Pages: 851-858
  • Peer Reviewed
• [Journal Article] TMS-induced artifacts on EEG can be reduced by rearrangement of the electrode's lead wire before recording (2011)
  • Author(s): Sekiguchi H., Takeuchi S., Kadota H., Kohno Y., Nakajima Y.
  • Journal Title: Clinical Neurophysiology 122[Accepted in Sep 8, 2010] Pages: 984-990
  • Peer Reviewed
• [Journal Article] TMS-induced artifacts on EEG can be reduced by rearrangement of the eiectrode's lead wire before recording. (2011)
  • Author(s): Sekiguchi H., Takeuchi S., Kadota H., Kohno Y., Nakajima Y.
  • Journal Title: Clinical Neurophysiology Volume: 122 Pages: 984-990
  • Peer Reviewed
• [Journal Article] Contraction history produces task-specific variations in spinal excitability in healthy human soleus muscle. (2011)
  • Author(s): Uematsu, A., Sekiguchi, H., Kobayashi, H., Hortobagyi, T., Suzuki, S.
  • Journal Title: Muscle & Nerve Volume: 43 Pages: 851-858
  • Peer Reviewed
• [Journal Article] The role of the dorsolateral prefrontal cortex in the inhibition of stereotyped responses. (2010)
  • Author(s): Kadota H, Sekiguchi H, Takeuchi S, Miyazaki M, Kohno Y, Nakajima Y.
  • Journal Title: Experimental Brain Research 203 Pages: 593-600
  • Peer Reviewed
• [Journal Article] An fMRI study of musicians with focal dystonia during tapping tasks (2010)
  • Author(s): Kadota H., Nakajima Y., Miyazaki M., Sekiguchi H., Kohno Y., Amako M., Arino H., Nemoto K., Sakai N.
  • Journal Title: Journal of Neurology 257 Pages: 1092-1098
  • Peer Reviewed
• [Journal Article] The role of the dorsolateral prefrontal cortex in the inhibition of stereotyped responses. (2010)
  • Author(s): Kadota H, Sekiguchi H, Takeuchi S, Miyazaki M, Kohno Y, Nakajima Y.
  • Journal Title: Experimental Brain Research Volume: 203 Pages: 593-600
  • Peer Reviewed
• [Journal Article] An fMRI study of musicians with focal dystonia during tapping tasks (2010)
  • Author(s): Hiroshi Kadota, Yasoichi Nakajima, Makoto Miyazaki, Hirofumi Sekieuchi, Yutaka Kohno, Masatoshi Amako, Hiroshi Arino, Koichi Nemoto, Naotaka Sakai
  • Journal Title: Journal of Neurology
  • Peer Reviewed
• [Journal Article] Enhanced excitability of the corticospinal pathway of the ankle extensor and flexor muscles during standing in humans (2009)
  • Author(s): Obata, H., Sekiguchi, H., Nakazawa, K., Ohtsuki, T.
  • Journal Title: Experimental Brain Research 197 Pages: 207-213
  • Peer Reviewed
• [Journal Article] Anterior prefrontal cortex activities during the inhibition of stereotyped responses in a neuropsychological rock-paper-scissors task (2009)
  • Author(s): Kadota, H., Nakajima,Y., Miyazaki, M., Sekiguchi, H., Kohno, Y., Kansaku, K.
  • Journal Title: Neuroscience Letters 453(1) Pages: 1-5
  • Peer Reviewed
• [Journal Article] Enhanced stretch reflex excitability of the soleus muscle in experienced swimmers (2009)
  • Author(s): Ogawa, T., Kim, G.H., Sekiguchi, H., Akai, M., Suzuki, S., Nakazawa, K.
  • Journal Title: European Journal of Applied Physiology 105(2) Pages: 199-205
  • Peer Reviewed
• [Journal Article] Enhanced excitability of the corticospinal pathway of the ankle extensorand flexor muscles during standing in humans (2009)
  • Author(s): Hiroki Obata, Hirofumi Sekieuchi, Kimitaka Nakazawa, Tatsuyuki Ohtsuki
  • Journal Title: Experimental Brain Research 197 Pages: 207-213
  • Peer Reviewed
• [Journal Article] 脳波電極リード線の再配置によるTMS-EEGの効果的なアーチファクト減弱法 (2009)
  • Author(s): 関口浩文, 竹内成生, 門田宏, 河野豊, 中島人十一
  • Journal Title: 臨床神経生理学(Japanese journal of clinical neuro physiology) 37 Pages: 365-366
• [Journal Article] 空間認知課題における予測と遂行評価 (2009)
  • Author(s): 竹内成生, 中島八十一, 門田宏, 望月芳子, 関口浩文
  • Journal Title: 臨床神経生理学(Japanese journal of clinical neuro physiology) 37 Pages: 350-350
• [Presentation] Motor learning of uni- and bi-manual grip force modulation (2010)
  • Author(s): Sekiguchi, H., Takeushi, S., Kadota, H., Nakazawa, K., Miyazaki, M., Uchida, S., Nozaki, D.
  • Organizer: 40^<th> Annual Meeting Neuroscience 2010
  • Place of Presentation: San Diego, U.S.A.
  • Year and Date: 2010-11-14
• [Presentation] The effects of TMS on the FB-ERN in time estimation task (2010)
  • Author(s): Takeuchi, S., Mochizuki, Y., Kadota, H., Sekiguchi. H., Kohno, Y., Nakajima, Y.
  • Organizer: 29^<th> International Congress of Clinical Neurophy siology
  • Place of Presentation: Kobe, Japan
  • Year and Date: 2010-11-01
• [Presentation] Time course of excitability in corticospinal tract after mirror therapy (2010)
  • Author(s): Kohno, Y., Sekiguchi, H., Kadota, H., Takeuchi, S., Ueno, T., Nagata, H., Nakajima, Y.
  • Organizer: 29^<th> International Congress of Clinical Neuraphy siology
  • Place of Presentation: Kobe, Japan
  • Year and Date: 2010-10-31
• [Presentation] TMS-induced artifacts on EEG can be reduced by rearrangement of the electrode's lead wire before recording (2010)
  • Author(s): Sekiguchi, H., Takeuchi, S., Kadota, H., Kohno, Y., Nakajima, Y.
  • Organizer: 29^<th> International Congress of Clinical Neurophysiology
  • Place of Presentation: Kobe, Japan
  • Year and Date: 2010-01-01
• [Presentation] Motor learning of uni- and bi-manual grip force modulation (2010)
  • Author(s): Sekiguchi, H., Takeushi, S., Kadota, H., Nakazawa, K., Miyazaki, M., Uchida, S., Nozaki, D.
  • Organizer: 40th Annual Meeting Neuroscience 2010, Abstract, 293.22.
  • Place of Presentation: San Diego, U.S.A.
• [Presentation] The effects of TMS on the FB-ERN in time estimation task (2010)
  • Author(s): Takeuchi, S., Mochizuki, Y., Kadota, H., Sekiguchi, H., Kohno, Y., Nakajima, Y.
  • Organizer: 29th International Congress of Clinical Neurophysiology, Clinical Neurophysiology, Vol.121.Suppl.1, S293.
  • Place of Presentation: Kobe, Japan
• [Presentation] Time course of excitability in corticospinal tract after mirror therapy (2010)
  • Author(s): Kohno, Y., Sekiguchi, H., Kadota, H., Takeuchi, S., Ueno, T., Nagata, H., Nakajima, Y.
  • Organizer: 29th International Congress of Clinical Neurophysiology, Clinical Neurophysiology, Vol.121.Suppl.1, S259.
  • Place of Presentation: Kobe, Japan
• [Presentation] TMS-induced artifacts on EEG can be reduced by rearrangement of the electrode's lead wire before recording (2010)
  • Author(s): Sekiguchi, H., Takeuchi, S., Kadota,H., Kohno, Y., Nakajima, Y.
  • Organizer: 29th International Congress of Clinical Neurophysiology, Clinical Neurophysiology, Vol.121.Suppl.1, S280.
  • Place of Presentation: Kobe, Japan
• [Presentation] 脳波電極リード線の再配置によるTMS-EEGの効果的なアーチファクト減弱法 (2009)
  • Author(s): 関口浩文, 竹内成生, 門田宏, 河野豊, 中島八十一
  • Organizer: 第39回日本臨床神経生理学会学術大会
  • Place of Presentation: 北九州国際会議場(小倉)
  • Year and Date: 2009-11-19
• [Presentation] 空間認知課題における予測と遂行評価 (2009)
  • Author(s): 竹内成生, 中島八十一, 門田宏, 望月芳子, 関口浩文
  • Organizer: 第39回日本臨床神経生理学会学術大会
  • Place of Presentation: 北九州国際会議場(小倉)
  • Year and Date: 2009-11-18
• [Presentation] Target-reaching and switching movements during suppression of the visual cortex in humans (2009)
  • Author(s): Ohki, Y., Shibuya, S., Sekiguchi, H., Kadota, H., Takeuchi, S., Sayadi, J., Nakajima, Y.
  • Organizer: XXXVI International Congress of Physiological Sciences
  • Place of Presentation: Kyoto, Japan