| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Research Abstract |
Skeletal muscle atrophy and hypertrophy involve the regulation of protein synthesis which is caused by alterations in mechanical stress against the muscle, which is indicated from data of denervation atrophy in rat and stretch-induced hypertrophy of cultured cell in this project. Furthermore, the disused-atrophy model of mouse tail-suspension has been established in our laboratory. This model will allow for more detail analyses on the relation between cell signaling and the recovery of muscle force generating capacity.
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