Application consideration of resting state functional connectivity for rehabilitation science.

• Project/Area Number: 21700570
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: International University of Health and Welfare
• Principal Investigator: UCHIDA Shinya 国際医療福祉大学, 保健医療学部, 講師 (90527011)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: リハビリテーション医学 / 機能的結合性 / 神経線維連絡 / 脳梁欠損 / MRI / 可塑性 / 脳梁無形成 / 安静状態

Research Abstract

The present study examined the relationship between functional connectivity during resting state and neural fiber connection using MRI. Two cases with agenesis of the corpus callosum showed patterns of interhemispheric functional connectivity which were similar to those of anatomically normal populations. Those two cases had normal intelligence and have maintained employment as well as social activities. Hence, the present study indicated a possibility that long-term organization during neural maturation would give rise to compensated brain mechanism even in those with agenesis of the corpus callosum.

Research Products

• [Presentation] 先天性脳梁欠損者における機能的結合性 (2011)
  • Author(s): 内田信也, ら
  • Organizer: 第1回国際医療福祉大学学会
  • Place of Presentation: 国際医療福祉大学(栃木県大田原市)
  • Year and Date: 2011-09-02
• [Presentation] 先天性脳梁欠損者における機能的結合性 (2011)
  • Author(s): 内田信也, 中原潔, 緑川晶, 倉岡康治, 齋藤慈子, 河村満, 中村克樹
  • Organizer: 第1回国際医療福祉大学大会
  • Place of Presentation: 栃木県大田原
• [Presentation] A subject with complete agenesis of the corpus callosum showing Interhemispheric functional connectivity. (2010)
  • Author(s): Uchida, S., et al.
  • Organizer: 第33回日本神経科学大会
  • Place of Presentation: 神戸コンベンションセンター
  • Year and Date: 2010-09-02
• [Presentation] Interhemispheric functional connectivity in a subject with complete Agenesis of the corpus callosum. (2010)
  • Author(s): Uchida, S., et al.
  • Organizer: 16th Annual Meeting of the Organization for Human Brain Mapping
  • Place of Presentation: Catalonia Palace of Congress, Barcelona, Spain
  • Year and Date: 2010-06-07
• [Presentation] 脳梁完全欠損者における半球間機能的結合性 (2010)
  • Author(s): 内田信也, 中原潔, 緑川晶, 倉岡康治, 齋藤慈子, 河村満, 中村克樹
  • Organizer: 第33回日本神経科学大会
  • Place of Presentation: 兵庫県神戸市
• [Presentation] Interhemispheric functional connectivity in a subject with complete agenesis of corpus callosum (2010)
  • Author(s): Uchida S., Nakahara K., Midorikawa A., Kuraoka K., Saito A., Kawamura M., Nakamura K.
  • Organizer: 16th annual meeting of the organization for human brain mapping
  • Place of Presentation: Barcelona, Spain