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Role of serotonergic network on thermoregulatory system

Research Project

Project/Area Number 21700596
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Physical education
Research InstitutionRikkyo University

Principal Investigator

ISHIWATA Takayuki  Rikkyo University, コミュニティ福祉学部, 准教授 (40435235)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords体温調節 / 神経伝達物質 / セロトニン / 腹側被蓋野 / マイクロダイアリシス
Research Abstract

It is suggested that brain serotonin (5-HT) is the main neurotransmitter in the thermoregulatory system. The purpose of present study was to clarify the role of 5-HT in the ventral tegmental area (VTA) on thermoregulatory system. We observed the change of 5- HT of VTA during heat or cold exposure. In addition, we observed the change of thermoregulatory responses when 5-HT in the VTA was increased. As a result, it was suggested that 5-HT in the VTA mainly regulates heat loss regulation.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (4 results)

All 2011

All Journal Article (2 results) Presentation (2 results)

  • [Journal Article] Role of serotonin in the ventral tegmental area on thermoregulation of freely moving rats2011

    • Author(s)
      Takayuki Ishiwata, Satomi Takatsu, Hiroshi Hasegawa, Shigeki Nomoto
    • Journal Title

      The Journal of Physiological Sciences, Supplement 1 61

      Pages: 243-243

    • Related Report
      2010 Final Research Report
  • [Journal Article] Role of serotonin in the ventral tegmental area on thermoregulation of freely moving rats2011

    • Author(s)
      Takayuki Ishiwata, Satomi Takatsu, Hiroshi Hasegawa, Shigeki Nomoto
    • Journal Title

      The Journal of Physiological Sciences, Supplement 1

      Volume: 61 Pages: 243-243

    • Related Report
      2010 Annual Research Report
  • [Presentation] 体温調節機構における腹側被蓋野のセロトニンの役割2011

    • Author(s)
      石渡貴之
    • Organizer
      第88回日本生理学会大会,第116回日本解剖学会総会・全国学術集会 合同大会(震災のため誌上発表)
    • Place of Presentation
      パシフィコ横浜・会議センター
    • Year and Date
      2011-03-29
    • Related Report
      2010 Final Research Report
  • [Presentation] 体温調節機構における腹側被蓋野のセロトニンの役割2011

    • Author(s)
      石渡貴之
    • Organizer
      第88回日本生理学会大会,第116回日本解剖学会総会・全国学術集会 合同大会
    • Place of Presentation
      パシフィコ横浜・会議センター(中止の為誌上報告)
    • Year and Date
      2011-03-29
    • Related Report
      2010 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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