Effects of physical activity level on hippocampal neurogenesis in rats.

• Project/Area Number: 21700654
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Sports science
• Research Institution: Osaka City University (2010); Osaka University (2009)
• Principal Investigator: NOMURA Sachiko Osaka City University, 大学院・医学研究科, 研究員 (30348784)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
• Keywords: スポーツ生化学 / 海馬ニューロン新生 / 運動 / 海馬 / ニューロン新生 / 神経栄養因子 / エピジェネティクス

Research Abstract

Previous studies have reported that exercise enhances neurogenesis in the hippocampus. In the present study, we explored whether the lack of muscle activity affect neurogenesis in rats using the hindlimb suspension model.

Research Products

• [Presentation] Effect of hindlimb suspension on hippocampal neurogenesis in weaned rats. (2010)
  • Author(s): S.Nomura, K.Kami, F.Kawano, Y.Oke, T.Ohira, R.Fujita, N.Naoya, Y.Ohira
  • Organizer: Experimental Biology Annual Meeting 2010
  • Place of Presentation: Anaheim, USA
  • Year and Date: 2010-04-26
• [Presentation] Effect of hindlimb suspension on hippocampal neurogenesis in weaned rats. (2010)
  • Author(s): Sachiko Nomura, Katsuya Kami, Fuminori Kawano, Yoshihiko Oke, Takashi Ohira, Ryo Fujita, Nakai Naoya, Yoshinobu Ohira
  • Organizer: Experimental Biology Annual Meeting
  • Place of Presentation: Anaheim, USA
  • Year and Date: 2010-04-26
• [Presentation] 後肢懸垂が発育期ラットの脳ニューロン新生に及ぼす影響 (2009)
  • Author(s): 野村幸子、上勝也、河野史倫、尾家慶彦、大平宇志、藤田諒、大平充宣
  • Organizer: 第55回日本宇宙航空環境医学会大会
  • Place of Presentation: 岐阜
  • Year and Date: 2009-11-14
• [Presentation] Hindlimb suspension impairs hippocampal neurogenesis in weaned rats. (2009)
  • Author(s): S.Nomura, K.Kami, F.Kawano, Y.Oke, N.Naoya, M.Terada, T.Ohira, K.Imaizumi, Y.Ohira
  • Organizer: The 36th Congress of the International Union of Physiological Sciences
  • Place of Presentation: Kyoto
  • Year and Date: 2009-07-29
• [Presentation] Hindlimb suspension impairs hippocampal neurogenesis in weaned rats (2009)
  • Author(s): Nomura S, Kami K, Kawano F, Oke Y, Naoya N, Terada M, Ohira T, Imaizumi K, Ohira Y
  • Organizer: The 36th Congress of the International Union of Physiological Sciences
  • Place of Presentation: Kyoto
  • Year and Date: 2009-07-29
• [Presentation] 離乳期ラット海馬ニューロン新生に及ぼす後肢懸垂の影響 (2009)
  • Author(s): 野村幸子、上勝也、河野史倫、尾家慶彦、大平宇志、藤田諒、大平充宣
  • Organizer: 第17回日本運動生理学会
  • Place of Presentation: 東京
  • Year and Date: 2009-07-25