| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Research Abstract |
The aim of this study was to clarify the effect of ageing and exercise training on α-actinin-3 in rat skeletal muscle. Our results suggest that ageing-induced muscle atrophy and fast-to-slow shift of the plantaris muscle accompanied with decrease in α-actinin-3, suggesting salcopenia might be associated with α-actinin-3.However, endurance exercise that we selected did not alter α-actinin-3 expression. Thus, endurance-type exercise may not be effective as intervention to α-actinin-3.
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