| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
Present study investigate whether the gene polymorphisms of PGC-1 and nuclear receptor affects endurance performance and muscular mitochondrial content. The Gly/Gly+Gly/Ser of PGC-1αgene polymorphism, and T/T+T/C of PPARδ gene T294C polymorphism, are significantly higher endurance performance than that of Ser/Ser and C/C, respectively. In exercise training study, the decrease of LDL cholesterol is greater in Gly/Gly than the Gly/Ser, and Ser/Ser. The improvement of lactate threshold intensity is higher in T/T than the T/C, and C/C.
However, those polymorphisms are not affected in muscular mitochondrial content.
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