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Changes of cerebral blood flow in elderly women during normal aging

Research Project

Project/Area Number 21700704
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Applied health science
Research InstitutionJapan Women's College of Physical Education

Principal Investigator

SATO Kohei  日本女子体育大学, 体育学部, 講師 (00409278)

Co-Investigator(Renkei-kenkyūsha) SADAMOTO Tomoko  日本女子体育大学, 体育学部, 教授 (30201528)
OOUE Anna  日本女子体育大学, 基礎体力研究所, 助教 (00550104)
Research Collaborator HIRASAWA Ai  日本女子体育大学, 基礎体力研究所, 技術職員
OGOH Shigehiko  東洋大学, 理工学部, 教授 (80553841)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords高齢者 / 脳血流量 / 体力 / 血圧 / 脳血流 / 運動トレーニング / 加齢 / 持久力 / 持久的能力
Research Abstract

The aim of this study was to determine whether the association between the resting cerebral blood flow and physical fitness in elderly women. The main finding of the present study was that total fitness level in elderly women was significantly correlated with resting cerebral blood flow. These finding suggest that the age-related reduction in cerebral blood flow is attenuated by maintain the high physical fitness level.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (42 results)

All 2012 2011 2010 2009 Other

All Journal Article (17 results) (of which Peer Reviewed: 17 results) Presentation (17 results) Book (4 results) Remarks (4 results)

  • [Journal Article] Differential blood flow responses to CO_2 in human internal and external carotid and vertebral arteries2012

    • Author(s)
      Sato, K., Sadamoto, T., Hirasawa, A., Oue, A., Subudhi, A., Miyazawa, T., Ogoh, S.
    • Journal Title

      J Physiol

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Differential blood flow responses to CO_2 in human internal and exter-nal carotid and vertebral arteries2012

    • Author(s)
      Sato, K., Sadamoto, T., Hirasawa, A., Oue, A., Subudhi, A., Miyazawa, T., Ogoh, S.
    • Journal Title

      Journal of Physiology

      Volume: (受理・掲載号未定)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The distribution of blood flow in the carotid and vertebral arteries during dynamic exercise in humans2011

    • Author(s)
      Sato, K., Ogoh, S., Hirasawa, A., Oue, A., Sadamoto, T.
    • Journal Title

      J Physiol

      Volume: 589 Pages: 2847-2856

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] The distribution of blood flow in the carotid and vertebral ar-teries during dynamic exercise in humans2011

    • Author(s)
      Sato, K, Ogoh, S., Hirasawa, A., Oue, A., Sadamoto, T.
    • Journal Title

      Journal of Physiology

      Volume: 589 Pages: 2847-2856

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The effect of phenylephrine on arterial and venous cerebral blood flo-w in healthy subjects2011

    • Author(s)
      Ogoh, S., Sato, K., Fisher, J.P., Seifert, T., Overgaard, M., Secher, N.H.
    • Journal Title

      Clin Physiol Funct Imaging

      Volume: 31 Issue: 6 Pages: 445-451

    • DOI

      10.1111/j.1475-097x.2011.01040.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The distribution of blood flow in the carotid and vertebral arteries during dynamic exercise in humans.2011

    • Author(s)
      Sato, K, Ogoh, S., Hirasawa, A., Oue, A., Sadarnoto, T.
    • Journal Title

      J Physiol

      Volume: (受理・掲載号未定)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Different blood flow responses to dynamic exercise between internal carotid artery and vertebral artery in women2010

    • Author(s)
      Sato, K., Sadamoto, T.
    • Journal Title

      J Appl Physiol

      Volume: 109 Pages: 864-869

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Different blood flow responses to dynamic exercise between internal carotid artery and vertebral artery in women.2010

    • Author(s)
      Sato, K., Sadamoto, T.
    • Journal Title

      J Appl Physiol

      Volume: 109 Pages: 864-869

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Aerobic exercise capacity and skeletal muscle volume after lower limb suspension with exercise countermeasure.2010

    • Author(s)
      Sato, K, Katayama, K., Hotta, N., Ishida, K., Akima, H
    • Journal Title

      Aviat Space Environ Med

      Volume: 81 Pages: 1-7

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Blood flow and arterial vessel diameter change during graded handgrip exercise indominant and non-dominant foreanns of tennis players.2010

    • Author(s)
      Kagaya A, Ohmori F, Okuyama S, Muraoka Y, Sato K.
    • Journal Title

      Adv Exp Med Biol. 662

      Pages: 365-370

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of deconditioning on the initial ventilatory and circulatory responses at the onset of exercise in man.2010

    • Author(s)
      Ishida K, Katayama K, Akima H, Iwase S, Sato K, Hotta N, Miyamura M.
    • Journal Title

      Adv Exp Med Biol. 669

      Pages: 319-322

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dynamic cerebral autoregulation during and after handgrip exercise in humans.2010

    • Author(s)
      Ogoh S, Sato K, Akimoto T, Oue A, Hirasawa A, Sadamoto T.
    • Journal Title

      J Appl Physiol. 108

      Pages: 1701-1705

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cerebrovascular response during heavy upper body exercise : effect of mode of ventilation on blood flow velocity in the middle cerebral artery.2010

    • Author(s)
      Sato, K., A.Hirasawa, N.Tsunoda, Y.Taniguchi, T.Sadamoto.
    • Journal Title

      Adv.Exp.Med.Biol. 662

      Pages: 347-352

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Influence of central command on cerebral blood flow at the onset of exercise in women.2009

    • Author(s)
      Sato K., Moriyama M., Sadamoto T.
    • Journal Title

      Exp Physiol. 93

      Pages: 1139-1146

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Central command and the increase in middle cerebral artery blood flow velocity during static arm exercise in women.2009

    • Author(s)
      Sato K, Sadamoto T, Ueda-Sasahara C, Shibuya K, Shimizu-Okuyama S, Osada T, Kamo M, Saito M, Kagaya A.
    • Journal Title

      Exp Physiol. 93

      Pages: 1132-1138

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cycle ergometer exercise to counteract muscle atrophy during unilateral lower limbsuspension.2009

    • Author(s)
      Akima H, Hotta N, Sato K, Ishida K, Koike T, Katayama K.
    • Journal Title

      Aviat Space Environ Med. 80

      Pages: 652-656

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Perceived exertion is not necessarily associated with altered brain activity during exercise.2009

    • Author(s)
      Shibuya K, Ueda C, Sato K, Shimizu-Okuyama S, Saito M, Kagaya A, Kamo M, Osada T, Sadamoto T.
    • Journal Title

      J Physiol Anthropol. 28

      Pages: 63-69

    • NAID

      110007162505

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 女性高齢者における脳血流量と体力レベルの関係性2011

    • Author(s)
      平澤愛, 佐藤耕平, 大上安奈, 定本朋子
    • Organizer
      第62回日本体育学会大会
    • Place of Presentation
      鹿児島
    • Year and Date
      2011-09-26
    • Related Report
      2011 Final Research Report
  • [Presentation] 女性高齢者における脳血流量と体力レベルの関係性2011

    • Author(s)
      平澤愛, 佐藤耕平, 大上安奈, 定本朋子
    • Organizer
      第62回日本体育学会大会
    • Place of Presentation
      鹿屋市,鹿児島県
    • Year and Date
      2011-09-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] 高齢期女性における総頸動脈血流量の経年的変化2011

    • Author(s)
      平澤愛, 佐藤耕平, 大上安奈, 中村泉, 定本朋子
    • Organizer
      第66回日本体力医学会大会
    • Place of Presentation
      山口
    • Year and Date
      2011-09-17
    • Related Report
      2011 Final Research Report
  • [Presentation] 起立ストレスに対する脳自己調節機能-内頸動脈と椎骨動脈との比較-2011

    • Author(s)
      佐藤耕平, 平澤愛, 宮澤大機, 小河繁彦
    • Organizer
      第66回日本体力医学会大会
    • Place of Presentation
      下関市,山口県
    • Year and Date
      2011-09-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] Elevation blood flow in common carotid artery with aerobic fitness in elderly women2011

    • Author(s)
      Hirasawa, A., Sato, K., Ooue, A., Nakamura, I., Sadamoto, T.
    • Organizer
      The 16th Annual Congress of the European College of Sport Science
    • Place of Presentation
      Liverpool, UK
    • Year and Date
      2011-07-04
    • Related Report
      2011 Final Research Report
  • [Presentation] Heterogeneous cerebrovascular responses to dynamic exercise in anatomically distinct cerebral arteries2011

    • Author(s)
      Sato, K., Hirasawa, A., Oue, A., Ogoh, S., Sadamoto, T.
    • Organizer
      The 57th American College of Sports Medicine
    • Place of Presentation
      Baltimore, USA
    • Year and Date
      2011-06-03
    • Related Report
      2011 Final Research Report
  • [Presentation] Heterogeneous cerebrovascular responses to dynamic exercise in anatomically disti-nct cerebral arteries2011

    • Author(s)
      Sato, K., Hirasawa, A., Oue, A., Ogoh, S., Sadamoto, T.
    • Organizer
      The 57th American College of Sports Medicine
    • Place of Presentation
      Baltimore, USA
    • Year and Date
      2011-06-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] 高齢者における血圧と総頸動脈血流量および脳血流配分比の関係性.2010

    • Author(s)
      佐藤耕平, 平澤愛, 中村泉, 定本朋子
    • Organizer
      第65回体力医学会
    • Place of Presentation
      千葉商科大学(千葉)
    • Year and Date
      2010-09-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] 動的運動時における椎骨動脈血流応答と呼気終末位CO2濃度との関係性2010

    • Author(s)
      佐藤耕平, 平澤愛, 定本朋子
    • Organizer
      日本体育学会第61回大会
    • Place of Presentation
      中京大学(愛知)
    • Year and Date
      2010-09-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] Central command and vertebral blood flow during static arm exercise in humans.2010

    • Author(s)
      Sato, K., Sadamoto, T.
    • Organizer
      The 57th American College of Sports Medicine
    • Place of Presentation
      Baltimore, USA
    • Year and Date
      2010-06-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] 最大努力のハンドグリップレジスタンストレーニングは疲労困憊に到る静的運動時の脳血流応答を亢進させる.2009

    • Author(s)
      佐藤耕平, 平澤愛, 斉藤満, 定本朋子
    • Organizer
      第64回日本体力医学会大会
    • Place of Presentation
      新潟
    • Year and Date
      2009-09-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] 高強度レジスタンストレーニングが静的握力発揮時の心拍応答に及ぼす影響.2009

    • Author(s)
      定本朋子, 佐藤耕平, 平澤愛, 斉藤満
    • Organizer
      第64回日本体力医学会大会
    • Place of Presentation
      新潟
    • Year and Date
      2009-09-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] 高強度レジスタンストレーニングが静的握力発揮時の腎動脈血流調節に及ぼす影響2009

    • Author(s)
      平澤愛, 佐藤耕平, 斉藤満, 山本幸弘, 定本朋子
    • Organizer
      第64回日本体力医学会大会
    • Place of Presentation
      新潟
    • Year and Date
      2009-09-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] 多段階掌握運動時における脳血流調節2009

    • Author(s)
      佐藤耕平, 平澤愛, 定本朋子
    • Organizer
      日本体育学会第60回記念大会
    • Place of Presentation
      広島
    • Year and Date
      2009-08-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] Role of central command in cerebral blood flow regulation during static exercise.2009

    • Author(s)
      Sato K., Sasahara C., Shibuya K., Hirasawa A., Okuyama S., Osada S., Kamo M., Saito M., Kagaya A., Sadamoto, T
    • Organizer
      The 36th International Congress of Physiological Sciences.
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2009-08-01
    • Related Report
      2009 Annual Research Report
  • [Presentation] Role of central command in the renal arterial blood flow responses during staticelbow flexion.2009

    • Author(s)
      Sadamoto T., Sato K., Hirasawa A., Sasahara C., Shibuya K., Saito M., Kamo M., Osada T., Kagaya A
    • Organizer
      The 14th Annual Congress of the European College of Sport Science.
    • Place of Presentation
      Oslo, Norway
    • Year and Date
      2009-06-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] Role of central command in middle cerebral blood flow velocity during static exercise in humans.2009

    • Author(s)
      Sato K., Sasahaza C., Shibuya K., Hirasawa A., Okuyama S., Osada S., Kamo M., Saito M., Kagaya A., Sadamoto T.
    • Organizer
      The 56th American college of Sports Medicine.
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2009-05-27
    • Related Report
      2009 Annual Research Report
  • [Book] 高齢者の脳機能と運動2012

    • Author(s)
      佐藤耕平, 平澤愛, 定本朋子
    • Publisher
      杏林書店
    • Related Report
      2011 Final Research Report
  • [Book] 身体運動と呼吸・循環機能2012

    • Author(s)
      佐藤耕平
    • Publisher
      真興交易医書出版
    • Related Report
      2011 Final Research Report
  • [Book] 運動生理学のニューエビデンス2010

    • Author(s)
      佐藤耕平, 小河繁彦
    • Publisher
      真興交易医書出版
    • Related Report
      2011 Final Research Report
  • [Book] 脳循環調節.運動生理学のニューエビデンス2010

    • Author(s)
      佐藤耕平, 小河繁彦
    • Total Pages
      460
    • Publisher
      真興交易医書出版
    • Related Report
      2010 Annual Research Report
  • [Remarks] 日本女子体育大学附属基礎体力研究所ホームページ

    • URL

      http://www.jwcpe.ac.jp/research/

    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://www.jwcpe.ac.jp/research/

    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://www.jwcpe.ac.jp/research/

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.jwcpe.ac.jp/research/

    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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