The effect of physical activity on immune senescence in elderly

• Project/Area Number: 21700705
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Applied health science
• Research Institution: Waseda University
• Principal Investigator: SHIMIZU Kazuhiro Waseda University, スポーツ科学学術院, 助手 (00508286)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: 運動 / 免疫機能 / 加齢 / ヘルスプロモーション / ストレスマネジメント / 加齢・老化

Research Abstract

The purpose of this study was to examine the effects of physical activity including exercise on immune function in elderly individuals.
Intensive exercise increased salivary defensin secretion in young individuals, suggesting defensin might response to exercise In elderly individuals, free-living daily physical activity might increase salivary defensin secretion. Consequently, physical activity might enhance immune function in elderly people.

Research Products

• [Presentation] 粘膜面における感染防御と運動-分泌型IgAを中心に- (2011)
  • Author(s): 秋本崇之, 清水和弘
  • Organizer: 第88回日本生理学会大会 第116回日本解剖学会総会・全国学術集会 合同大会
  • Place of Presentation: 震災のため誌上開催
• [Presentation] 新しいコンディション指標-唾液を用いたコンディション評価-.シンポジウム1:アスリートのコンディション評価 現状と将来 (2010)
  • Author(s): 清水和弘
  • Organizer: 第21回日本臨床スポーツ医学会学術集会
  • Place of Presentation: 茨城
  • Year and Date: 2010-11-06
• [Presentation] 新しいコンディション指標-唾液を用いたコンディション評価- (2010)
  • Author(s): 清水和弘
  • Organizer: 第21回日本臨床スポーツ医学会学会大会
  • Place of Presentation: つくば市(招待講演)
  • Year and Date: 2010-11-06
• [Presentation] 分泌型IgAからみたオープンウィンドウ仮説.ワークショップ10:運動をするとカゼをひきやすくなるのか?-オープンウィンドウ仮説への挑戦- (2010)
  • Author(s): 清水和弘
  • Organizer: 第65回日本体力医学会大会
  • Place of Presentation: 千葉
  • Year and Date: 2010-09-17
• [Presentation] Influence of 3 consecutive days of high intensity exercise on resting salivary antibacterial peptides in young male subjects. (2010)
  • Author(s): Shimizu K, Tanimura Y, Hanaoka Y, Suzuki S, Nokura K, Eda N, Ajisaka R, Kono I, Akama T.
  • Organizer: European College of Sport Science 15th annual meeting
  • Place of Presentation: Antalya, Turkey
  • Year and Date: 2010-06-25
• [Presentation] Influence of 3 consecutive days of high intensity exercise on resting salivary antibacterial peptides in young male subjects (2010)
  • Author(s): Kazuhiro Shimizu, Yuko Tanimura, Yukichi Hanaoka
  • Organizer: 15th annual Congress of European College of Sport Science
  • Place of Presentation: Antalya(トルコ)
  • Year and Date: 2010-06-25
• [Book] 21世紀スポーツ大辞典(スポーツとホメオスタシス)(中村敏雄, 高橋健夫, 寒川恒夫, 友添秀則(編))
  • Author(s): 清水和弘,赤間高雄
  • Publisher: 大修館書店(印刷中)