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Studies on search and action mechanism of new functional substances of a constituent of Porphyra yezoensis

Research Project

Project/Area Number 21700768
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Eating habits, studies on eating habits
Research InstitutionPrefectural University of Kumamoto

Principal Investigator

TOMOYORI Hiroko  熊本県立大学, 環境共生学部・食健康科学科, 講師 (10347700)

Project Period (FY) 2009 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥8,863,207 (Direct Cost: ¥6,817,852、Indirect Cost: ¥2,045,355)
Fiscal Year 2012: ¥673,207 (Direct Cost: ¥517,852、Indirect Cost: ¥155,355)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2009: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Keywords糖尿病 / 低栄養 / 機能性食品 / 海藻 / 海苔 / 栄養学 / 食品 / 脂質
Research Abstract

In order to clarify the effect on the lipid absorption of Nori, we administered Nori sample to rats. The sample was obtained by heating rapeseed oil and Nori fine powder (RNAO). The lipid concentration in the blood compared to the control group, RNAO were high. Therefore, in order to reveal the agent, we subjected to a lipid load test using water-soluble dietary fiber (porphyran) extracted from Nori, unexpectedly lipid absorption was inhibited. Moreover, this effect was investigated whether it was depended on the viscosity of Nori solution. It was shown that it is not intended to promote lipid absorption by the viscosity. These results were measured lipid level in blood. In order to evaluate more accurately, the next experiment was examined absorption into the lymph. As a result, lymph flow and the phospholipid concentration were not influenced, but lipid concentration became higher. These observations suggest that RNAO may promote the lipid absorption. Further, we advanced the separation and purification of the insulin-like action substance from Nori, but did not lead to identification of the active substance

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (3 results)

All 2011 2010

All Presentation (3 results)

  • [Presentation] スサビノリ由来成分の脂質吸収促進作用に関する研究2011

    • Author(s)
      友寄博子、近藤昌次、淺川牧夫
    • Organizer
      日本栄養・食糧学会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-03
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] スサビノリ由来成分のインスリン様作用2010

    • Author(s)
      友寄博子、近藤昌次、淺川牧夫
    • Organizer
      日本栄養・食糧学会
    • Place of Presentation
      宮崎
    • Year and Date
      2010-09-25
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] 海藻由来成分のインスリン様作用2010

    • Author(s)
      友寄博子、淺川牧夫
    • Organizer
      日本農芸化学会
    • Place of Presentation
      熊本
    • Year and Date
      2010-09-17
    • Related Report
      2012 Final Research Report 2010 Annual Research Report

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Published: 2009-04-01   Modified: 2019-07-29  

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