Molecular function of radiation-induced mammary carcinoma-related genes/microRNAs in three dimensional culture system
Project/Area Number |
21710058
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Risk sciences of radiation/Chemicals
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Research Institution | Hiroshima University |
Principal Investigator |
IIZUKA Daisuke Hiroshima University, 原爆放射線医科学研究所, 助教 (00455388)
|
Project Period (FY) |
2009 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
|
Keywords | 放射線誘発乳がん / 三次元培養 / マイクロRNA / 放射線発がん |
Research Abstract |
In this study, I focused on radiation-induced mammary carcinoma-related genes/microRNAs, and I analyzed whether these genes/microRNAs formed aberrant mammary ductal structure in three dimensional culture systems. The aberrant mammary ductal structure was not observed by introducing these microRNAs in MCF-10A cells, suggesting that these microRNAs have no function at least on the formation of mammary duct.
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Report
(3 results)
Research Products
(12 results)