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Intake estimation of organophosphate flame retardants on school children

Research Project

Project/Area Number 21710068
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Risk sciences of radiation/Chemicals
Research InstitutionSaga University

Principal Investigator

UENO Daisuke  Saga University, 農学部, 講師 (60423604)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords有機リン系難燃剤 / PFRs / ダスト / 小学校 / シックハウス(シックスクール)症候群 / 摂取量 / 低減法 / ガスクロマトグラフィー質量分析計(GC / MS) / シックスクール症候群 / 難燃剤・可塑剤 / 有機リン系・臭素系 / 環境汚染 / 室内環境 / ハウスダスト / 学校環境 / 低減技術
Research Abstract

In order to quantify oral intake of organophosphate flame retardants (PFRs), housedust samples collected from elementary school in Saga city, Japan were employed for chemical analysis. PFRs were detected from all the housedust samples analyzed. Among the PFRs detected, tris butoxyethyl phosphate (T(BxEt)P) was the predominate compound and concentration range was 3600-1900000ng/g dry weight. PFRs concentrations in housedust were compared between those from elementary school and private house. Significant higher concentrations were found in housedust samples from elementary school. Among the housedust samples from elementary school, the highest concentration of total PFRs was found in "school A". Percent contributions of individual compounds to total PFRs concentrations in housedust sample from school A showed higher contribution of (T(BxEt)P), and those were from 50-99%. It is known that (T(BxEt)P) has been used for the products of floor wax. Higher contribution of (T(BxEt)P) in housedust from elementary school would reflect the frequent use of floor wax containing this chemical. In order to evaluate the adverse effect of PFRs, intake amount of PFRs through housedust was estimated. By comparing to tolerable daily intake (TDI) of PFRs, intake amount of T(BxEt)P by children through housedust could be exceeded 19 times higher than TDI.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (22 results)

All 2011 2010 2009 Other

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (5 results) Book (7 results) Remarks (3 results)

  • [Journal Article] Visualization and Direct Counting of Individual Denitrifying Bacterial Cells in Soil by nirK-Targeted Direct in situ PCR2011

    • Author(s)
      Ryuda, N., Hashimoto, T., Ueno, D., Inoue, K., Someya, T.
    • Journal Title

      Microbes and Environments

      Volume: 26 Pages: 74-80

    • NAID

      10028099025

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Spatial distribution of hexabromocyclododecanes (HBCDs), polybrominated diphenyl ethers (PBDEs) and organochlorines in bivalves from Japanese coastal waters.2010

    • Author(s)
      Ueno, D., Isobe, T., Ramu, K., Tanabe, S., Alaee, M., Marvin, C., Inoue, K., Someya, T., Miyajima, T., Kodama, H., Nakata, H.
    • Journal Title

      Chemosphere 78

      Pages: 1213-1219

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Spatial distribution of hexabromocyclododecanes (HBCDs), polybrominated diphenyl ethers (PBDEs) and organochlorines in bivalves from Japanese coastal waters2010

    • Author(s)
      Ueno, D., Isobe, T., Ramu, K., Tanabe, S., Alaee, M., Marvin, C., Inoue, K., Someya, T., Miyajima, T., Kodama, H., Nakata, H.
    • Journal Title

      Chemosphere

      Volume: 78 Pages: 1213-1219

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Spatial distribution of hexabromocyclododecanes (HBCDs), polybrominated diphenyl ethers (PBDEs) and organochlorines in bivalves from Japanese coastal waters2010

    • Author(s)
      Ueno, D., Isobe, T., Ramu, K., Tanabe, S., Alaee, M., Marvin, C., Inoue, K., Someya, T., Miyajima, T., Kodama, H., Nakata, H.
    • Journal Title

      Chemosphere 78

      Pages: 1213-1219

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 佐賀環境フォーラムにおけるシックスクール問題への取り組み2009

    • Author(s)
      市場正良, 高橋達也, 山下善功, 高石恵子, 西村晃一, 蒲池将史, 近藤敏弘, 松本明子, 上野大介, 宮島徹
    • Journal Title

      日本衛生学雑誌 64

      Pages: 26-31

    • NAID

      10024477449

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Direct viable count combined with fluorescence in situ hybridization (DVC-FISH) for specific enumeration of viable Escherichia coli in cow manure2009

    • Author(s)
      Wu, S., Ueno, D., Inoue, K., Someya, T.
    • Journal Title

      Microbes Environ. 24

      Pages: 33-38

    • NAID

      110007131151

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inactivation of Escherichia coli in soil by solarization2009

    • Author(s)
      WU, S., Nishihara, M., Kawasaki, Y., Yokoyama, A., Matsuura, K., Koga, T., Ueno, D., Inoue, K., Someya, T.
    • Journal Title

      Soil Sci. Plant Nutr. 55

      Pages: 258-263

    • NAID

      110007522807

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 小学校室内ダストを介した有機リン系難燃・可塑剤の摂取量推定2010

    • Author(s)
      勢島宏基, 市場正良, 滝上英孝, 梶原夏子, 井上興一, 染谷孝, 上野大介
    • Organizer
      室内環境学会学術大会
    • Place of Presentation
      横浜
    • Year and Date
      2010-12-09
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 人工香料による母乳の汚染現状把握とその摂取経路の推定2010

    • Author(s)
      牛島愛, 中田晴彦, 井上興一, 染谷孝, 上野大介
    • Organizer
      室内環境学会学術大会
    • Place of Presentation
      横浜
    • Year and Date
      2010-12-09
    • Related Report
      2010 Final Research Report
  • [Presentation] GC/MSデータベース法を用いた環境試料中有機化学物質の検索2010

    • Author(s)
      上野大介, 野島宏明, 井上興一, 染谷孝, 東房健一, 中島晋也
    • Organizer
      第19回環境化学討論会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-06-21
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] イガイを用いた環太平洋域の難分解PPCPs汚染モニタリング2010

    • Author(s)
      中田晴彦, 篠原竜一, 中澤優介, 渡部真文, 磯部友彦, 田辺信介, Kannan, K., 上野大介
    • Organizer
      第19回環境化学討論会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-06-21
    • Related Report
      2010 Final Research Report
  • [Presentation] 日本人母乳および脂肪組織中人工香料の蓄積現状と取り込み経路の推定2009

    • Author(s)
      上野大介, 井上興一, 染谷孝, 龍田典子, 宮島徹, 兒玉宏樹, 市場正良, 国末達也, 尹浩信, 丸尾圭志, 中田晴彦
    • Organizer
      第18回環境化学討論会
    • Place of Presentation
      つくば
    • Year and Date
      2009-06-09
    • Related Report
      2010 Final Research Report
  • [Book] 環境毒性学(環境動態・水界・POPs, 農薬など有機化合物)(渡邉泉, 久野勝治, ed.)(東京)2011

    • Author(s)
      上野大介
    • Publisher
      朝倉書店
    • Related Report
      2010 Final Research Report
  • [Book] 環境毒性学(起源推定・分布パターン:汚染源と平面的, 立体的分布の特徴・有機汚染物質)(渡邉泉, 久野勝治, ed.)(東京)2011

    • Author(s)
      上野大介
    • Publisher
      朝倉書店
    • Related Report
      2010 Final Research Report
  • [Book] 環境毒性学2011

    • Author(s)
      上野大介
    • Total Pages
      260
    • Publisher
      朝倉出版
    • Related Report
      2010 Annual Research Report
  • [Book] 環境科学(水の汚染, in地球環境テキストブック)(吉原利一, ed.)(東京)2010

    • Author(s)
      上野大介
    • Publisher
      オーム社
    • Related Report
      2010 Final Research Report
  • [Book] 地球環境テキストブック 環境科学2010

    • Author(s)
      上野大介
    • Total Pages
      345
    • Publisher
      オーム社
    • Related Report
      2010 Annual Research Report
  • [Book] Interdisciplinary Studies on Environmental Chemistry-Environmental Research in Asia(Synthetic musk fragrances in human breast milk and adipose tissue from Japan)(Obayashi, Y., Isobe, T., Subramanian, A., Suzuki, S., Tanabe, S., ed.)(Tokyo)2009

    • Author(s)
      Ueno, D., Moribe, M., Inoue, K., Someya, T., Ryuda, N., Ichiba, M., Miyajima, T., Kunisue, T., In, H., Maruo, K., Nakata, H.
    • Publisher
      Terrapub
    • Related Report
      2010 Final Research Report
  • [Book] Interdisciplinary Studies on Environmental Chemistry-Environmental Research in Asia(Bioaccumulation of Dioxins in the Benthic Fish from Hiroshima Bay)(Obayashi, Y., Isobe, T., Subramanian, A., Suzuki, S.and Tanabe, S., ed.)(Tokyo)2009

    • Author(s)
      Tanaka, H., Kono, K., Ueno, D.
    • Publisher
      Terrapub
    • Related Report
      2010 Final Research Report
  • [Remarks] ホームページ等

    • URL

      http://environbio.ag.saga-u.ac.jp/ueno/index.html

    • Related Report
      2010 Final Research Report
  • [Remarks]

    • URL

      http://environbio.ag.saga-u.ac.jp/ueno/index.html

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://environbio.ag.saga-u.ac.jp/ueno/index.html

    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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