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Identification of vertebrate phylotypic stage by transcriptome analysis

Research Project

Project/Area Number 21710195
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field 基礎ゲノム科学
Research InstitutionThe Institute of Physical and Chemical Research

Principal Investigator

IRIE Naoki  The Institute of Physical and Chemical Research, 形態進化研究グループ, 研究員 (10536121)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywordsシステムゲノム / ゲノム調節 / 進化発生学 / トランスクリプトーム / バイオインフォマティクス / EvoDevo / ファイロティピック段階
Research Abstract

Formulation of the relationship between ontogeny and phylogeny (=evolution) has been controversial between scientists. Here we have analyzed gene expression profiles of embryos of mice, chicken, xenopus, and zebrafish, and clarified that pharyngula stages are the most conserved stages, and the developmental hourglass model best explains the relationship between ontogeny and phylogeny.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (21 results)

All 2011 2010 2009 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (15 results) Book (3 results) Remarks (1 results)

  • [Journal Article] Comparative transcriptome analysis reveals vertebrate phylotypic period during organogenesis2011

    • Author(s)
      Irie,N., Kuratani,S
    • Journal Title

      Nature Communications Mar.

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparative transcriptome analysis reveals vertebrate phylotypic period during organogenesis2011

    • Author(s)
      Naoki Irie, Shigeru Kuratani
    • Journal Title

      Nature Communications

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] The Developmental hourglass model and phylotype of the vertebrates.2011

    • Author(s)
      Naoki Irie, Shigeru Kuratani
    • Organizer
      Joint meeting of the GFE and JSDB
    • Place of Presentation
      Dresden, Germany
    • Related Report
      2010 Final Research Report
  • [Presentation] Molecular identification of vertebrate phylotypic stage and epigenetic insights of vertebrate embryogenesis, CDB Symposium 20112011

    • Author(s)
      Naoki Irie, Shigeru Kuratani
    • Organizer
      Epigenetic Landscape in Development and Disease
    • Place of Presentation
      Kobe
    • Related Report
      2010 Final Research Report
  • [Presentation] Molecular identification of the vertebrate phylotypic stage, 20th CDB Meeting2011

    • Author(s)
      Naoki Irie, Shigeru Kuratani
    • Organizer
      Molecular Bases for Evolution of Complex Traits
    • Place of Presentation
      Kobe
    • Related Report
      2010 Final Research Report
  • [Presentation] The Developmental hourglass model and phylotype of the vertebrates2011

    • Author(s)
      Naoki Irie, Shigeru Kuratani
    • Organizer
      Joint meeting of the GFE and JSDB
    • Place of Presentation
      Dresden, Germany
    • Related Report
      2010 Annual Research Report
  • [Presentation] Molecular identification of vertebrate phylotypic stage and epigenetic insights of vertebrate embryogenesis2011

    • Author(s)
      Naoki Irie, Shigeru Kuratani
    • Organizer
      CDB Symposium 2011 "Epigenetic Landscape in Development and Disease"
    • Place of Presentation
      Kobe
    • Related Report
      2010 Annual Research Report
  • [Presentation] Molecular identification of the vertebrate phylotypic stage.2011

    • Author(s)
      Naoki Irie, Shigeru Kuratani
    • Organizer
      20th CDB Meeting "Molecular Bases for Evolution of Complex Traits"
    • Place of Presentation
      Kobe
    • Related Report
      2010 Annual Research Report
  • [Presentation] Testing phylotype hypothesis and structural insights of vertebrate embryogenesis.2010

    • Author(s)
      入江直樹、倉谷滋
    • Organizer
      BMB 2010(1T7-8 & 1P-1139)
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Related Report
      2010 Final Research Report
  • [Presentation] Testing phylotype hypothesis and structural insights of vertebrate embryogenesis2010

    • Author(s)
      Naoki Irie, Shigeru Kuratani
    • Organizer
      BMB 2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] 脊椎動物ファイロタイプ仮説検証と発生学的構造特性の示唆2010

    • Author(s)
      入江直樹、倉谷滋
    • Organizer
      生命情報科学若手の会第2回研究会
    • Place of Presentation
      三島
    • Year and Date
      2010-10-09
    • Related Report
      2010 Final Research Report
  • [Presentation] カメの甲の新規形態パターンをもたらした発生機構の解明にむけて公開シンポジウム「複合適応形質の進化」2010

    • Author(s)
      入江直樹、倉谷滋
    • Organizer
      領域会議
    • Place of Presentation
      東京
    • Year and Date
      2010-09-17
    • Related Report
      2010 Final Research Report
  • [Presentation] カメの甲の新規形態パターンをもたらした発生機構の解明にむけて2010

    • Author(s)
      入江直樹, 倉谷滋
    • Organizer
      公開シンポジウム「複合適応形質の進化」
    • Place of Presentation
      東京
    • Year and Date
      2010-09-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] 脊椎動物ファイロタイプは原形論的な幻想か?2010

    • Author(s)
      入江直樹、倉谷滋
    • Organizer
      日本進化学会第12回大会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] 脊椎動物ファイロタイプは原形論的な幻想か?2010

    • Author(s)
      入江直樹, 倉谷滋
    • Organizer
      日本進化学会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] Ontogeny and phylogeny of the vertebrates : testing the developmental hourglass model by transcriptome dynamycs comparisons.2010

    • Author(s)
      Naoki Irie, Shigeru Kuratani
    • Organizer
      Joint meeting of the SFBD and JSDB
    • Place of Presentation
      Paris
    • Related Report
      2010 Annual Research Report
  • [Presentation] Is earlier developmental stage more conserved than later stages?~analysis of zebrafish transcriptome during embryogenesis~2009

    • Author(s)
      入江直樹
    • Organizer
      第42回発生生物学会
    • Place of Presentation
      新潟市
    • Related Report
      2009 Annual Research Report
  • [Book] 実験医学2011

    • Author(s)
      八谷剛史、入江直樹、荒川和晴
    • Publisher
      Close Up実験法<羊土社>次世代シークエンサー活用術
    • Related Report
      2010 Final Research Report
  • [Book] 実験医学2011

    • Author(s)
      入江直樹、連利博
    • Publisher
      母児間マイクロキメリズムが問いかける自己と他者免疫学・再生医学・臨床医学への展開,Update Review <羊土社>29(6)
    • Related Report
      2010 Final Research Report
  • [Book] 母児間マイクロキメリズムが問いかける自己と他者(実験医学)2011

    • Author(s)
      入江直樹
    • Total Pages
      6
    • Publisher
      羊土社 実験医学
    • Related Report
      2010 Annual Research Report
  • [Remarks] ホームページ等

    • URL

      http://www.cdb.riken.jp/emo/mem/NI_web/NI_index.html

    • Related Report
      2010 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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