Direct Observation of Hydrogen Transfer during the Model for Enzymatic Reactions by Pulsed Neutron Diffraction Analysis.

• Project/Area Number: 21750007
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Physical chemistry
• Research Institution: Ibaraki University
• Principal Investigator: HOSOYA Takaaki 茨城大学, 工学部, 助教 (80435601)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: 中性子回折 / 結晶相反応 / 水素・プロトン移動 / J-PARC / 結晶構造解析

Research Abstract

N-Salicylideneanilines are well known to exhibit photochromism (from yellow to red) in the solid state. To observe the hydrogen atom transfer during the photochromic reaction clearly, we carried out the neutron diffraction measurement at BL03 iBIX in J-PARC.

Research Products

• [Journal Article] Hydrogen-bond network and pH sensitivity in transthyretin : neutron crystal structure of human transthyretin (2012)
  • Author(s): Yokoyama, T., Mizuguchi, M., 他9名
  • Journal Title: Journal of Structural Biology Volume: 177 Issue: 2 Pages: 283-290
  • DOI: 10.1016/j.jsb.2011.12.022
  • Peer Reviewed
• [Journal Article] A wavelength-shifting-fibre-based scintillator neutron detector implemented with the median point calculation method (2012)
  • Author(s): T.Nakamura, T.Kawasaki, T.Hosoya, K.Toh, M.Ebine, A.Birumachi, K.Sakasai, K.Soyama, M.Katagiri
  • Journal Title: Journal of Instrumentation Volume: 7 Issue: 02 Pages: C02003-C02003
  • DOI: 10.1088/1748-0221/7/02/c02003
  • Peer Reviewed
• [Journal Article] Strong Effect of Yb Filling Fraction on the Magnetic Ground Sate of the Filled Skutterudite YbFe4Sb12 (2011)
  • Author(s): T.SAITO
  • Journal Title: J.Phys.Soc.Jpn. Volume: 80 Issue: 6 Pages: 63708-63711
  • DOI: 10.1143/jpsj.80.063708
  • Peer Reviewed
• [Journal Article] 化学における単結晶中性子構造解析 (2010)
  • Author(s): 細谷孝明, 大原高志
  • Journal Title: RADIOISOTOPES Volume: Vol.59, No.4 Pages: 279-287
  • NAID: 10026244796
  • Peer Reviewed
• [Journal Article] Neutron Structure Analysis Using the IBARAKI Biological Crystal Diffractometer (iBIX) at J-PARC (2010)
  • Author(s): Tanaka I, Kusaka K, Hosoya T, (他7名、3番目)
  • Journal Title: Acta Crystallogr D Volume: Vol. 66 Pages: 1194-1197
  • Peer Reviewed
• [Journal Article] 化学における単結晶中性子構造解析 (2010)
  • Author(s): 細谷孝明、大原高志
  • Journal Title: RADIOISOTOPES 59(印刷中)
  • NAID: 10026244796
• [Presentation] Developments for Upgrades of 2-Dimension Scintillator Detector System, Data Acquisition Electronics and Software for J-PARC (2011)
  • Author(s): Takaaki HOSOYA
  • Organizer: IUCr 2011 (XXII Congress of the International Union of Crystallography)
  • Place of Presentation: Madrid, Spain
  • Year and Date: 2011-08-28
• [Presentation] Developments for Upgrades of 2-Dimension Scintilla tor Detector System, Data Acquisition Electronics and Software for J-PARC (2011)
  • Author(s): 細谷孝明
  • Organizer: IUCr2011 (XXII Congress of the International Union of Crystallography)
  • Place of Presentation: マドリード(スペイン)
  • Year and Date: 2011-08-28
• [Presentation] Preliminary Neutron Powder Diffraction Analysis of a Meta-stable Colored Form in Photochromic Crystal using iMATERIA in J-PARC (2011)
  • Author(s): Takaaki HOSOYA
  • Organizer: IUCr 2011 (XXII Congress of the International Union of Crystallography)
  • Place of Presentation: Madrid, Spain
  • Year and Date: 2011-08-27
• [Presentation] Preliminary Neutron Powder Diffraction Analysis of a Meta-stable Colored Form in Photochromic Crystal using iMATERIA in J-PARC (2011)
  • Author(s): 細谷孝明
  • Organizer: IUCr2011 (XXII Congress of the International Union of Crystallography)
  • Place of Presentation: マドリード(スペイン)
  • Year and Date: 2011-08-27