The elucidation of color-tuning mechanism in Human red, green, and blue visual pigments and its application to medicine and engineering
| Project/Area Number |
21750019
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Physical chemistry
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| Research Institution | Kyoto University |
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Principal Investigator |
FUJIMOTO Kazuhiro Kyoto University, 大学院・理学研究科, 研究員 (00511255)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 生物物理 / 量子化学 / 生物・生体工学 / 励起状態 |
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| Research Abstract |
1. Color-tuning mechanism in Human red (HR), green (HG), and blue (HB) visual pigments was theoretically clarified in amino-acid level. The difference in absorption spectra between HR and HG could be explained in terms of direction of three hydroxyl residues in HR. 2. Mechanisms of color tuning in the M state of bacteriorhodopsin and in xanthorhodopsin were also investigated, which were compared with those in human visual pigments. 3. To analyze the mechanisms, new theoretical methods were developed.
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Report
(3 results)
Research Products
(19 results)
