Exploitation of the unique reactivity of diazocarbonyl compounds for the development of practical synthetic methods
| Project/Area Number |
21750041
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Organic chemistry
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| Research Institution | Kyoto University |
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Principal Investigator |
HASHIMOTO Takuya Kyoto University, 大学院・理学研究科, 助教 (20437198)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | ジアゾ化合物 / 酸触媒 / 触媒的不斉合成 / キラルブレンステッド酸 / キラルルイス酸 / アジリジン / 不斉補助基 / 不斉合成 |
|---|
| Research Abstract |
This research project was aimed at the development of novel synthetic methods based on the use of α-diazocarbonyl compounds, as it was anticipated to reveal straightforward ways for the preparation of complex molecules. This study led to the finding of novel synthetic methods for valuable synthetic building blocks, such as seven-membered carbocycles, β-keto carbonyl compounds and aziridines, which are commonly seen in anticancer drugs and other biologically active materials.
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Report
(3 results)
Research Products
(29 results)
