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New non-destructive laser desorption/ionization mass spectrometry with ultra high sensitivity by using surface plasmon excitation

Research Project

Project/Area Number 21750079
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Analytical chemistry
Research InstitutionTokyo Metropolitan University

Principal Investigator

SHIBAMOTO Kohei  首都大学東京, 大学院・理工学研究科, 助教 (50457834)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords表面プラズモン / レーザー / イオン化法 / 金ナノ微粒子 / 超高感度
Research Abstract

In this project, I had carried out understanding of desorption/ionization mechanism of our new non-destructive laser desorption/ionization mass spectrometry with ultra high sensitivity by using surface plasmon excitation, and then succeeded in abstraction of main three effects related to the mechanism, which are electromagnetic enhancement effect, charge transfer effect and localized heat effect. Further, by using obtained many findings, I succeeded in improvement of our method with background free analysis.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (51 results)

All 2011 2010 2009

All Journal Article (4 results) (of which Peer Reviewed: 2 results) Presentation (39 results) Book (4 results) Patent(Industrial Property Rights) (4 results)

  • [Journal Article] Laser Desorption Ionization Mass Spectrometry by Using Surface Plasmon Excitation on Gold Nanoparticle2009

    • Author(s)
      K. Shibamoto, K. Sakata K. Nagoshi and T. Korenaga
    • Journal Title

      J. Phys. Chem

      Volume: 113 Pages: 17774-17779

    • Related Report
      2011 Final Research Report
  • [Journal Article] Ionization Mechanism in Surface Plasmon Enhanced Laser Desorption/Ionization2009

    • Author(s)
      Keishiro Nagoshi, Kazuhiro Sakata, Kohei Shibamoto and Takashi Korenaga
    • Journal Title

      J. Surf. Sci. Nanotech.

      Volume: 7 Pages: 93-96

    • NAID

      130004439125

    • Related Report
      2011 Final Research Report
  • [Journal Article] Laser Desorption Ionization Mass Spectrometry by Using Surface Plasmon Excitation on Gold Nanoparticle2009

    • Author(s)
      K.Shibamoto, K.Sakata K.Nagoshi, T.Korenaga
    • Journal Title

      Journal of Physical Chemistry C 113

      Pages: 17774-17779

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ionization Mechanism in Surface Plasmon Enhanced Laser Desorption/Ionization2009

    • Author(s)
      Keishiro Nagoshi, Kazuhiro Sakata, Kohei Shibamoto, Takashi Korenaga
    • Journal Title

      e-Journal of Surface Science and Nanotechnology 7

      Pages: 93-96

    • NAID

      130004439125

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Approach for Characterization of Surface Reaction on Alkanethiol Molecules Chemisorbed on Gold Nanoparticles by using Laser Desorption Ionization Mass Spectrometry2011

    • Author(s)
      名越慶士郎、芝本幸平、伊永隆史
    • Organizer
      JAIMA discussion on Analytical Science and Technology
    • Place of Presentation
      幕張(千葉)
    • Year and Date
      2011-09-17
    • Related Report
      2011 Final Research Report
  • [Presentation] Study for a mechanism of neutral sugar chain fragmentations in laser desorption/ionization mass spectrometry on titania surface2011

    • Author(s)
      藤田隆史、芝本幸平、伊永隆史
    • Organizer
      JAIMA discussion on Analytical Science and Technology
    • Place of Presentation
      幕張メッセ(千葉県)
    • Year and Date
      2011-09-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] Approach for Characterization of Surface Reaction on Alkanethiol Molecules Chemisorbed on Gold Nanoparticles by using Laser Desorption Ionization Mass Spectrometry2011

    • Author(s)
      名越慶士郎、芝本幸平、伊永隆史
    • Organizer
      JAIMA discussion on Analytical Science and Technology
    • Place of Presentation
      幕張メッセ(千葉県)
    • Year and Date
      2011-09-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] Study of Fragmentaton Process of Neutral Sugar Chain in Laser Desorption/Ionization on Titania Surface2011

    • Author(s)
      Takashi Fujita, Kohei Shibamoto, Tatsuya Fujino, Takashi Korenaga
    • Organizer
      ICAS2011 (International Congress on Analytical Science 2011)
    • Place of Presentation
      Kyoto International Conference Center
    • Year and Date
      2011-05-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] Detection Behavior of Resonantly-excited Adsorbed Molecules oa Gold Nanoparticle Surface in Two-laser Desorption Ionization Mass Spectrometry2011

    • Author(s)
      Kohei Shibamoto, Takayuki Matsuoka, Takashi Korenaga
    • Organizer
      ICAS2011 (International Congress on Analytical Science 2011)
    • Place of Presentation
      Kyoto International Conference Center
    • Year and Date
      2011-05-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] Approach for Characterization of Surface Reaction on Alkanethiol Molecules Chemisorbed on Gold Nanoparticles by Using Laser Desorption Ionization Mass Spectrometry2011

    • Author(s)
      Keishiro Nagoshi, Kohei Shibamoto, Tatsuya Fujino, Takashi Korenaga
    • Organizer
      ICAS2011 (International Congress on Analytical Science 2011)
    • Place of Presentation
      Kyoto International Conference Center
    • Year and Date
      2011-05-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] 特異的な光応答性を持つ微粒子で作製した機能性薄膜を用いた表面支援レーザー脱離イオン化法最先端質量分析研究の未来と戦略2011

    • Author(s)
      芝本幸平
    • Organizer
      日本質量分析学会春季シンポジウム
    • Place of Presentation
      東京虎ノ門
    • Year and Date
      2011-05-19
    • Related Report
      2011 Final Research Report
  • [Presentation] 特異的な光応答性を持つ微粒子で作製した機能性薄膜を用いた表面支援レーザー脱離イオン化法2011

    • Author(s)
      芝本幸平
    • Organizer
      日本質量分析学会春季シンポジウム「最先端質量分析研究の未来と戦略」(第137回日本質量分析学会関東談話会)
    • Place of Presentation
      東京・虎ノ門発明会館ホール(招待講演)
    • Year and Date
      2011-05-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] Approach for Characterization of Surface Reaction on Alkanethiol Molecules Chemisorbed on Gold Nanoparticles by Using Laser Desorption Ionization Mass Spectrometry2011

    • Author(s)
      Keishiro Nagoshi, Kohei Shibamoto, Tatsuya Fujino, Takashi Korenaga
    • Organizer
      International Congress on Analytical Science 2011
    • Place of Presentation
      Kyoto
    • Related Report
      2011 Final Research Report
  • [Presentation] Detection Behavior of Resonantly-excited Adsorbed Molecules on Gold Nanoparticle Surface in Two-laser Desorption Ionization Mass Spectrometry2011

    • Author(s)
      Kohei Shibamoto, Takayuki Matsuoka, Takashi Korenaga
    • Organizer
      International Congress on Analytical Science 2011
    • Place of Presentation
      Kyoto
    • Related Report
      2011 Final Research Report
  • [Presentation] 機能性ナノ微粒子薄膜の作製とその応用2010

    • Author(s)
      芝本幸平
    • Organizer
      ナノテク部会第39回研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-08
    • Related Report
      2011 Final Research Report
  • [Presentation] 機能性ナノ微粒子薄膜の作製とその応用2010

    • Author(s)
      芝本幸平
    • Organizer
      ナノテク部会第39回研究会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2010-11-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 共鳴励起された金ナノ微粒子表面吸着種の状態を評価する2光波レーザー脱離イオン化質量分析法2010

    • Author(s)
      松岡隆之、芝本幸平、藤野竜也、伊永隆史
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-16
    • Related Report
      2011 Final Research Report
  • [Presentation] アルカンチオール修飾金属ナノ微粒子表面を用いた新しいレーザー脱離イオン化質量分析法2010

    • Author(s)
      名越慶士郎、芝本幸平、藤野竜也、伊永隆史
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-16
    • Related Report
      2011 Final Research Report
  • [Presentation] アルカンチオール修飾金属ナノ微粒子表面を用いた新しいレーザー脱離イオン化質量分析法2010

    • Author(s)
      名越慶士郎、芝本幸平、藤野竜也、伊永隆史
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学
    • Year and Date
      2010-09-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] 金ナノ微粒子を表面修飾するアルカンチオールのSALDI-MS検出2010

    • Author(s)
      名越慶士郎、芝本幸平、伊永隆史
    • Organizer
      第58回質量分析総合討論会
    • Place of Presentation
      つくば
    • Year and Date
      2010-06-16
    • Related Report
      2011 Final Research Report
  • [Presentation] レーザー照射方法とイオン化基板開発の立場からのレーザー脱離イオン化法の分析性能向上へのアプローチ2010

    • Author(s)
      芝本幸平、名越慶士郎、藤田隆史、松岡隆之、清水伸幸、古屋大輔、伊永隆史
    • Organizer
      第58回質量分析総合討論会
    • Place of Presentation
      つくば
    • Year and Date
      2010-06-16
    • Related Report
      2011 Final Research Report
  • [Presentation] 金ナノ微粒子を表面修飾するアルカンチオールのSALDI-MS検出2010

    • Author(s)
      名越慶士郎、芝本幸平、伊永隆史
    • Organizer
      第58回質量分析総合討論会
    • Place of Presentation
      つくば市
    • Year and Date
      2010-06-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] アルカンチオール修飾金属ナノ微粒子表面を用いた新しいレーザー脱離イオン化質量分析法2010

    • Author(s)
      芝本幸平、名越慶士郎、藤田隆史、松岡隆之、清水伸幸、古屋大輔、伊永隆史
    • Organizer
      第58回質量分析総合討論会
    • Place of Presentation
      つくば市(招待講演)
    • Year and Date
      2010-06-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] 表面修飾金属ナノ微粒子のLDI-MSにおけるmetal-thiolクラスターイオンの検出挙動と表面プラズモン励起との関連2010

    • Author(s)
      名越慶士郎、芝本幸平、伊永隆史
    • Organizer
      第78回分析化学討論会
    • Place of Presentation
      島根
    • Year and Date
      2010-05-16
    • Related Report
      2011 Final Research Report
  • [Presentation] レーザー脱離イオン化質量分析法における金ナノ微粒子表面吸着種の検出挙動と共鳴励起状態との相関2010

    • Author(s)
      松岡隆之、芝本幸平、伊永隆史
    • Organizer
      第78回分析化学討論会
    • Place of Presentation
      島根
    • Year and Date
      2010-05-16
    • Related Report
      2011 Final Research Report
  • [Presentation] 表面修飾金属ナノ微粒子のLDI-MSにおけるmetal-thiolクラスターイオンの検出挙動と表面プラズモン励起との関連2010

    • Author(s)
      名越慶士郎、芝本幸平、伊永隆史
    • Organizer
      第78回分析化学討論会
    • Place of Presentation
      島根大学
    • Year and Date
      2010-05-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] レーザー脱離イオン化質量分析法における金ナノ微粒子表面吸着種の検出挙動と共鳴励起状態との相関2010

    • Author(s)
      松岡隆之、芝本幸平、伊永隆史
    • Organizer
      第78回分析化学討論会
    • Place of Presentation
      島根大学
    • Year and Date
      2010-05-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] Study on resonantl-excited state of Crystal Violet molecule adsorbed on gold nanoparticle surface by using LDI mass spectrometry with pulse and CW double laser system2010

    • Author(s)
      Takayuki Matsuoka, Kohei Shibamoto, Tatsuya Fujino, Takashi Korenaga
    • Organizer
      International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Hawaii
    • Related Report
      2011 Final Research Report
  • [Presentation] Detection of alkanethiol-gold complex anions desorbed from chemically-modified gold nanoparticle surface by using LDI-MS2010

    • Author(s)
      Keishiro Nagoshi, Kohei Shibamoto, Tatsuya Fujino, Takashi Korenaga
    • Organizer
      International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Hawaii
    • Related Report
      2011 Final Research Report
  • [Presentation] Study on resonantl-excited state of Crystal Violet molecule adsorbed on gold nanoparticle surface by using LDI mass spectrometry with pulse and CW double laser system2010

    • Author(s)
      Takayuki Matsuoka, Kohei Shibamoto, Tatsuya Fujino, Takashi Korenaga
    • Organizer
      2010 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Hawaii City
    • Related Report
      2010 Annual Research Report
  • [Presentation] Detection of alkanethiol-gold complex anions desorbed from chemically-modified gold nanoparticle surface by using LDI-MS2010

    • Author(s)
      Keishiro Nagoshi, Kohei Shibamoto, Tatsuya Fujino, Takashi Korenaga
    • Organizer
      2010 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Hawaii City
    • Related Report
      2010 Annual Research Report
  • [Presentation] 金ナノ微粒子2次元アレイ構造体基板を利用したレーザー脱離イオン化質量分析法の応用2009

    • Author(s)
      名越慶士郎、芝本幸平、伊永隆史
    • Organizer
      日本分析化学会第58年会
    • Place of Presentation
      北海道大学
    • Year and Date
      2009-09-25
    • Related Report
      2011 Final Research Report
  • [Presentation] 金ナノ微粒子2次元アレイ構造体基板を利用したレーザー脱離イオン化質量分析法の応用2009

    • Author(s)
      名越慶士郎、芝本幸平、伊永隆史
    • Organizer
      日本分析化学会 第58年会
    • Place of Presentation
      北海道大学
    • Year and Date
      2009-09-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] 微弱光源により共鳴励起された試料分子の状態を評価するレーザー脱離イオン化質量分析法2009

    • Author(s)
      松岡隆之、芝本幸平、伊永隆史
    • Organizer
      日本分析化学会第58年会
    • Place of Presentation
      北海道大学
    • Year and Date
      2009-09-24
    • Related Report
      2011 Final Research Report
  • [Presentation] 微弱光源により共鳴励起された試料分子の状態を評価するレーザー脱離イオン化質量分析法2009

    • Author(s)
      松岡隆之、芝本幸平、伊永隆史
    • Organizer
      日本分析化学会 第58年会
    • Place of Presentation
      北海道大学
    • Year and Date
      2009-09-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] 無機ナノ微粒子の特異的な光応答性が与えるレーザー脱離イオン化機構への影響評価2009

    • Author(s)
      芝本幸平、名越慶士郎、松岡隆之、伊永隆史
    • Organizer
      日本分析化学会第70回分析化学討論会
    • Place of Presentation
      和歌山大学
    • Year and Date
      2009-05-17
    • Related Report
      2011 Final Research Report
  • [Presentation] 無機ナノ微粒子の特異的な光応答性が与えるレーザー脱離イオン化機構への影響評価2009

    • Author(s)
      芝本幸平、名越慶士郎、松岡隆之、伊永隆史
    • Organizer
      日本分析化学会 第70回分析化学討論会
    • Place of Presentation
      和歌山大学
    • Year and Date
      2009-05-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] 表面プラズモン励起を利用したレーザー脱離イオン化法の脱離イオン化機構における熱の影響2009

    • Author(s)
      松岡隆之、芝本幸平、伊永隆史
    • Organizer
      日本質量分析学会第57回質量分析総合討論会
    • Place of Presentation
      大阪市
    • Year and Date
      2009-05-15
    • Related Report
      2011 Final Research Report
  • [Presentation] 表面プラズモン励起を利用したレーザー脱離イオン化法の脱離イオン化機構における熱の影響2009

    • Author(s)
      松岡隆之、芝本幸平、伊永隆史
    • Organizer
      日本質量分析学会 第57回質量分析総合討論会
    • Place of Presentation
      大阪市
    • Year and Date
      2009-05-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] 金ナノ微粒子上に誘起される表面プラズモン励起を利用したSALDI法における増強電磁場の寄与2009

    • Author(s)
      名越慶士郎、芝本幸平、伊永隆史
    • Organizer
      日本質量分析学会第57回質量分析総合討論会
    • Place of Presentation
      大阪市
    • Year and Date
      2009-05-14
    • Related Report
      2011 Final Research Report
  • [Presentation] 金ナノ微粒子上に誘起される表面プラズモン励起を利用したSALDI法における増強電磁場の寄与2009

    • Author(s)
      名越慶士郎、芝本幸平、伊永隆史
    • Organizer
      日本質量分析学会 第57回質量分析総合討論会
    • Place of Presentation
      大阪市
    • Year and Date
      2009-05-14
    • Related Report
      2009 Annual Research Report
  • [Presentation] 生体分子研究の未来とそれを可能にするMS日本質量分析学会BMS研究会2009

    • Author(s)
      芝本幸平
    • Organizer
      第36回BMSコンファレンス
    • Place of Presentation
      高知市
    • Related Report
      2011 Final Research Report
  • [Presentation] 生体分子研究の未来とそれを可能にするMS2009

    • Author(s)
      芝本幸平(招待講演)
    • Organizer
      日本質量分析学会BMS研究会、第36回BMSコンファレンス
    • Place of Presentation
      高知市
    • Related Report
      2009 Annual Research Report
  • [Book] 生命科学のための分析化学 第8章、9章、11章、12章 63-86、105-132ページ2011

    • Author(s)
      伊永隆史 編著, 芝本幸平分担執筆
    • Total Pages
      172
    • Publisher
      化学同人
    • Related Report
      2010 Annual Research Report
  • [Book] 新材料・新素材シリーズ「金ナノテクノロジー-その基礎と応用-(Gold Nanotechnology : Fundamentals and Applications)」2009

    • Author(s)
      春田正毅
    • Publisher
      シーエムシー出版
    • Related Report
      2011 Final Research Report
  • [Book] 新材料・新素材シリーズ「プラズモンナノ材料の最新技術(Latest Trends in Plasmonic Nanomaterials)」2009

    • Author(s)
      山田淳
    • Publisher
      シーエムシー出版
    • Related Report
      2011 Final Research Report
  • [Book] 新材料・新素材シリーズ「プラズモンナノ材料の最新技術(Latest Trends in Plasmonic Nanomaterials)」第5章計測・センシング応用技術 質量分析への応用展開204~2132009

    • Author(s)
      山田淳監修 芝本幸平分担執筆
    • Total Pages
      10
    • Publisher
      シーエムシー出版
    • Related Report
      2009 Annual Research Report
  • [Patent(Industrial Property Rights)] 金属ナノ微粒子表面の有機分子の解析方法2011

    • Inventor(s)
      芝本幸平、名越慶士郎、伊永隆史
    • Industrial Property Rights Holder
      芝本幸平、伊永隆史
    • Industrial Property Number
      2009-205617
    • Filing Date
      2011
    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] 金属ナノ微粒子表面の有機分子の解析方法2009

    • Inventor(s)
      芝本幸平、名越慶士郎、伊永隆史
    • Industrial Property Rights Holder
      芝本幸平、伊永隆史
    • Industrial Property Number
      2009-205617
    • Filing Date
      2009
    • Related Report
      2009 Annual Research Report
  • [Patent(Industrial Property Rights)] 金ナノ微粒子を2次元最密充填させた新規イオン化基板の開発2009

    • Inventor(s)
      芝本幸平、伊永隆史、名越慶士郎
    • Industrial Property Rights Holder
      芝本幸平、伊永隆史
    • Acquisition Date
      2009
    • Related Report
      2009 Annual Research Report
  • [Patent(Industrial Property Rights)] 質量分析における試料の調整方法2009

    • Inventor(s)
      芝本幸平、伊永隆史、谷昌美
    • Industrial Property Rights Holder
      芝本幸平、伊永隆史
    • Acquisition Date
      2009
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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