The development of catalytic cross-couplings using anisole derivatives
| Project/Area Number |
21750100
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Synthetic chemistry
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| Research Institution | Osaka University |
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Principal Investigator |
TOBISU Mamoru 大阪大学, 工学研究科, 特任講師(常勤) (60403143)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 均一系触媒 / 遷移金属錯体 / 不活性結合切断 / 炭素-酸素結合切断 / ニッケル触媒 / 還元的切断 / ヒドロシラン / アミノ化 / アニソール / クロスカップリング |
|---|
| Research Abstract |
Inert phenol derivatives, such as anisole, can be employed as an aryl halide surrogate. The key to success is the combined use of a nickel catalyst and bulky and electron-rich ligands. The Suzuki-Miyaura type reaction using organoboron reagents, amination using secondary amines, and reductive cleavage using hydrosilane have been developed.
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Report
(3 results)
Research Products
(6 results)
