Development and Application of Functional Micelles Bearing Helical Polymer Chains in the Core

• Project/Area Number: 21750118
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Polymer chemistry
• Research Institution: Kanazawa University
• Principal Investigator: MAEDA Katsuhiro Kanazawa University, 物質化学系, 准教授 (90303669)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
• Keywords: らせん / キラリティー / ミセル / ブロック共重合体 / 円二色性

Research Abstract

Amphiphilic block copolymers consisting of a hydrophobic polyisocyanate chain with an optically active terminal group with a hydrophilic poly(ethylene glycol) chain were successfully synthesized. It was demonstrated that the copolymers formed spherical micelles in aqueous solution and the helical sense excess of the polyisocyanate chain was amplified in the core of the micelles over that in THF due to the reduction in population of the helical reversals. Amphiphilic block copolymers consisting of a hydrophobic optically active polythiophene chain with a hydrophilic poly(acrylic acid) chain were also synthesized and these copolymers were found to self-assemble into micelles in water and exhibit a characteristic ICD in the π-π^^* transition region due to the formation of supramolecular chiral aggregates in the core.

Research Products

• [Presentation] Synthesis of anamphiphilic block copolymer bearing anoptically active π-conjugated polymer chain and the chiroptical properties of its micelle (2010)
  • Author(s): Katsuhiro Maeda, Satoru Nozaki, TomoyukiIkai, Shigeyoshi Kanoh
  • Organizer: The 2010 International Chemical Congress of Pacific Basin Societies (Pacifichem 2010)
  • Place of Presentation: Hawaii Convention Center(USA)
  • Year and Date: 2010-12-17
• [Presentation] Synthesis of an amphiphilic block copolymer bearing an optically active π-conjugated polymer chain and the chiroptical properties of its micelle (2010)
  • Author(s): Katsuhiro Maeda, Satoru Nozaki, Tomoyuki Ikai, Shigeyoshi Kanoh
  • Organizer: The 2010 International Chemical Congress of Pacific Basin Societies (Pacifichem 2010)
  • Place of Presentation: Hawaii Convention Center (USA)
  • Year and Date: 2010-12-17
• [Presentation] 光学活性なポリイソシアナート鎖を有する両親媒性ブロック共重合体の合成とそのキロプティカル特性 (2010)
  • Author(s): 荒川愛、前田勝浩、井改知幸、加納重義
  • Organizer: 第59回高分子討論会
  • Place of Presentation: 北海道大学(北海道)
  • Year and Date: 2010-09-15
• [Presentation] Synthesis ofamphiphilic block copolymers bearing anpolythiophene chain and chiropticalproperties of their micelles (2010)
  • Author(s): Katsuhiro Maeda, Satoru Nozaki, Tomoyuki Ikai, Shigeyoshi Kanoh
  • Organizer: 22nd International Symposium on Chirality(Chirality 2010; ISCD-22)
  • Place of Presentation: Sapporo Convention Center (Hokkaido)
  • Year and Date: 2010-07-13
• [Presentation] Synthesisof an amphiphilic diblock copolymers bearingan helical polyisocyanate chain and theirchiroptical properties (2010)
  • Author(s): Megumi Arakawa, Katsuhiro Maeda, Tomoyuki Ikai, Shigeyoshi Kanoh
  • Organizer: 22nd International Symposium on Chirality (Chirality 2010;ISCD-22)
  • Place of Presentation: Sapporo ConventionCenter (Hokkaido)
  • Year and Date: 2010-07-13
• [Presentation] Synthesis of an amphiphilic diblock copolymers bearing an helical polyisocyanate chain and their chiroptical properties (2010)
  • Author(s): Megumi Arakawa, Katsuhiro Maeda, Tomoyuki Ikai, Shigeyoshi Kanoh
  • Organizer: 22nd International Symposium on Chirality (Chirality 2010 ; ISCD-22)
  • Place of Presentation: Sapporo Convention Center (Hokkaido)
  • Year and Date: 2010-07-13
• [Presentation] Synthesis of amphiphilic block copolymers bearing an polythiophene chain and chiroptical properties of their micelles (2010)
  • Author(s): Katsuhiro Maeda, Satoru Nozaki, Tomoyuki Ikai, Shigeyoshi Kanoh
  • Organizer: 22nd International Symposium on Chirality (Chirality 2010 ; ISCD-22)
  • Place of Presentation: Sapporo Convention Center (Hokkaido)
  • Year and Date: 2010-07-13
• [Presentation] 光学活性なπ-共役高分子鎖を有する両親媒性ブロック共重合体の合成とそのキロプティカル特性 (2010)
  • Author(s): 埜崎哲、前田勝浩、井改知幸、加納重義
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 近畿大学本部キャンパス(大阪府)
  • Year and Date: 2010-03-28
• [Remarks] ホームページ等
  • URL: http://kohka.ch.t.kanazawa-u.ac.jp/lab5/lab5.html6