| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Research Abstract |
As a present method to analyze the redox state in a living thing, an ESR spatiotemporal imaging technique is applied to a small animal receiving a nitroxyl radical as a spin probe. In this method, however, the accurate images are not obtained when various radicals co-exist or the ESR line shape changes. In this paper, the development of the shield case with low eddy current and the field gradient coils with high speed response is reported in order to realize the modulated gradient method using the loop-gap resonator for a small animal. The spatial resolution was determined to be about 6.8 mm at the field gradient of 0.12 mT/mm. The separation of the EPR spectra of two types of radicals was also made.
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