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Breast Cancer Diagnosis by Optical Imaging with Inverse Problem of Source Estimation

Research Project

Project/Area Number 21760312
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Measurement engineering
Research InstitutionThe University of Electro-Communications

Principal Investigator

OKAWA Shinpei  The University of Electro-Communications, 大学院・情報理工学研究科, 助教 (20432049)

Co-Investigator(Renkei-kenkyūsha) YAMADA Yukio  電気通信大学, 大学院・情報理工学研究科, 教授 (10334583)
Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords信号処理 / 逆問題 / 拡散光トモグラフィ / 蛍光トモグラフィ / 乳がん
Research Abstract

The algorithms to solve the inverse problems in the optical imaging using near-infrared light for diagnoses of breast cancer were studied. The technique for reconstructing fluorescent light sources in biological media by use of spatial filter was proposed. The method to reduce noise in the time-resolved measurement data using maximum a priori estimation was also developed. The proposed methods were validated with the numerical simulations and the phantom experiments. Efficient arrangement of the light sources and detectors for diffuse optical tomography was also investigated.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (12 results)

All 2011 2010 2009

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (9 results)

  • [Journal Article] Reduction of Poisson noise in measured time-resolved data for time-domain diffuse optical tomography2011

    • Author(s)
      S.Okawa, Y.Endo, Y.Hoshi, Y.Yamada
    • Journal Title

      Medical and Biological Engineering and Computing DOI: 10.1007/s11517-011-0774-7

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Reconstruction of fluorescence/bioluminescence sources in biological medium with spatial filter2010

    • Author(s)
      S.Okawa, Y.Yamada
    • Journal Title

      Optics Express 13(12)

      Pages: 13151-13172

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Reconstruction of fluorescence/bioluminescence sources in biological medium with spatial filter2010

    • Author(s)
      Shinpei Okawa, Yukio Yamada
    • Journal Title

      Optics Express

      Volume: 13 Pages: 13151-13172

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Effect of the Arragngement of Optodes for 3D Diffuse Optical Tomography2011

    • Author(s)
      K.Uchida, S.Okawa, K.Masamoto, Y.Hoshi, Y.Yamada
    • Organizer
      Proc.of the ASME/JSME 2011 8th Thermal Engineering Joint Conference AJTEC2011-44480
    • Place of Presentation
      Honolulu, Hawaii, USA.
    • Related Report
      2010 Final Research Report
  • [Presentation] 3次元拡散光トモグラフィのシミュレーション2010

    • Author(s)
      内田和浩
    • Organizer
      日本機械学会 第22回バイオエンジニアリング講演会
    • Place of Presentation
      岡山理科大学
    • Year and Date
      2010-01-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] Source Reconstruction with Spatial Filter and Reduction of Artifacts in Fluorescence/Bioluminescence Diffuse Optical Tomography2010

    • Author(s)
      S.Okawa, Y.Yamada
    • Organizer
      Proc.of SICE Annual Conference 2010 3223-3224
    • Place of Presentation
      Taipei, Taiwan.
    • Related Report
      2010 Final Research Report
  • [Presentation] Reduction of Poisson Noise for Time-Resolved Diffuse Optical Measurement2010

    • Author(s)
      S.Okawa, Y.Yamada
    • Organizer
      Proc.of SICE Annual Conference 2010 91-592
    • Place of Presentation
      Taipei, Taiwan.
    • Related Report
      2010 Final Research Report
  • [Presentation] 3次元拡散光トモグラフィのシミュレーション2010

    • Author(s)
      内田和浩, 松橋翔子, 星詳子, 大川晋平, 山田幸生
    • Organizer
      第23回バイオエンジニアリング講演会講演論文集 366
    • Place of Presentation
      岡山
    • Related Report
      2010 Final Research Report
  • [Presentation] Source Reconstruction with Spatial Filter and Reduction of Artifacts in Fluorescence/Bioluminescence Diffuse Optical Tomography2010

    • Author(s)
      Shinpei Okawa, Yukio Yamada
    • Organizer
      SICE Annual Conference 2010
    • Place of Presentation
      Taiwan
    • Related Report
      2010 Annual Research Report
  • [Presentation] Reduction of Poisson Noise for Time-Resolved Diffuse Optical Measurement2010

    • Author(s)
      Shinpei Okawa, Yukio Yamada
    • Organizer
      SICE Annual Conference 2010
    • Place of Presentation
      Taiwan
    • Related Report
      2010 Annual Research Report
  • [Presentation] 3D light source reconstruction with spatial filter for fluorescence/bioluminescence diffuse optical tomography2009

    • Author(s)
      Shinpei Okawa
    • Organizer
      European Conference on Biomedical Optics
    • Place of Presentation
      Munich, Germany
    • Year and Date
      2009-06-14
    • Related Report
      2009 Annual Research Report
  • [Presentation] 3D light source reconstruction with spatial filter for fluorescence/bioluminescence diffuse optical tomography2009

    • Author(s)
      S.Okawa, Y.Yamada
    • Organizer
      Proc.of SPIE Vol.7369, Progress in Biomedical Optics and Imaging 10(45) 736916
    • Place of Presentation
      Munich, Germany.
    • Related Report
      2010 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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