Project/Area Number |
21760605
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Properties in chemical engineering process/Transfer operation/Unit operation
|
Research Institution | The University of Tokyo (2010) Kogakuin University (2009) |
Principal Investigator |
AKAMATSU Kazuki The University of Tokyo, 工学部, 助教 (50451795)
|
Project Period (FY) |
2009 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
Keywords | マイクロカプセル / ミクロスフィア / 膜乳化 / SPG膜 / キトサン / 酵素 / 生分解性 / ドラッグデリバリーシステム / アルギン酸 / 単分散 |
Research Abstract |
Microcapsules were prepared with alginate or chitosan, which are biocompatible polymers, by using the membrane emulsification technique. The detailed study on preparation condition enabled us to control the average diameter, monodispersity and the hollow structure of the microcapsules. Furthermore, a novel type of self-degradable microcapsules were successfully developed and demonstrated by encapsulating the enzymes that can decompose the shell polymers of the microcapsules.
|