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Highly selective colorimetric sensing for ionic species in aqueous media with newly-synthesized molecular sensors

Research Project

Project/Area Number 21760619
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Reaction engineering/Process system
Research InstitutionOsaka University

Principal Investigator

SHIRAISHI Yasuhiro  Osaka University, 太陽エネルギー化学研究センター, 准教授 (70343259)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords分子センサー / 発色 / 発光 / イオン種 / シアン化物イオン / スピロピラン / 蛍光 / フッ化物イオン / 水銀イオン / 銅イオン
Research Abstract

In this research subject, we have tried to develop the molecular sensors that enable rapid and accurate detection of cations, anions, and amino acids dissolved in aqueous media. Conventional molecular sensors hold several disadvantages such as 1) low selectivity for targeted ions, 2) long response time, and 3) weak spectral response. We developed several molecular sensors that overcome these issues based on our unique strategy for molecular design.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (58 results)

All 2011 2010 2009 Other

All Journal Article (33 results) (of which Peer Reviewed: 33 results) Presentation (23 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Highly Sensitive Cyanide Anion Detection with a Coumarin-Spiropyran Conjugate as a Fluorescent Receptor2011

    • Author(s)
      Yasuhiro Shiraishi, Shigehiro Sumiya, Takayuki Hirai
    • Journal Title

      Chemical Communications 47

      Pages: 4953-4955

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Rapid Colorimetric Sensing of Cyanide Anion in Aqueous Media with a Spiropyran Derivative Containing a Dinitrophenolate Moiety2011

    • Author(s)
      Yasuhiro Shiraishi, Masataka Itoh, Takayuki Hirai
    • Journal Title

      Tetrahedron Letters 52

      Pages: 1515-1519

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A BODIPY-Based Fluorescent Chemodosimeter for Cu(II) Driven by Oxidative Dehydrogenation Mechanism2011

    • Author(s)
      Dongping Wang, Yasuhiro Shiraishi, Takayuki Hirai
    • Journal Title

      Chemical Communications 47

      Pages: 2673-2675

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Colorimetric Response of a Spiropyran Derivative to Anions in Aqueous or Organic Media2011

    • Author(s)
      Yasuhiro Shiraishi, Masataka Itoh, Takayuki Hirai
    • Journal Title

      Tetrahedron 67

      Pages: 891-897

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cu(II)-Selective Fluorescence of a Bis-Quinolylimine Derivative2011

    • Author(s)
      Chizuru Ichimura, Yasuhiro Shiraishi, Takayuki Hirai
    • Journal Title

      Journal of Photochemistry and Photobiology A : Chemistry

      Volume: 217 Pages: 253-258

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Colorimetric Response of a Spiropyran Derivative to Anions in Aqueous or Organic Media2011

    • Author(s)
      Yasuhiro Shiraishi, Masataka Itoh, Takayuki Hirai
    • Journal Title

      Tetrahedron

      Volume: 67 Pages: 891-897

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A BODIPY-Based Fluorescent Chemodosimeter for Cu(II) Driven by Oxidative Dehydrogenation Mechanism2011

    • Author(s)
      Dongping Wang, Yasuhiro Shiraishi, Takayuki Hirai
    • Journal Title

      Chemical Communications

      Volume: 47 Pages: 2673-2675

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rapid Colorimetric Sensing of Cyanide Anion in Aqueous Media with a Spiropyran Derivative Containing a Dinitrophenolate Moiety2011

    • Author(s)
      Yasuhiro Shiraishi, Masataka Itoh, Takayuki Hirai
    • Journal Title

      Tetrahedron Letters

      Volume: 52 Pages: 1515-1519

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cu(II)-Selective Fluorescence of a Bis-Quinolylimine Derivative2010

    • Author(s)
      Chizuru Ichimura, Yasuhiro Shiraishi, Takayuki Hirai
    • Journal Title

      Journal of Photochemistry & Photobiology, A : Chemistry 217

      Pages: 253-2584

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Local Viscosity Analysis of Pluronic Triblock Copolymer Micelle with Cyanine Dyes as Fluorescent Probe2010

    • Author(s)
      Yasuhiro Shiraishi, Takuya Inoue, Takayuki Hirai
    • Journal Title

      Langmuir 26

      Pages: 17505-17512

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Thermal Isomerization of Spiropyran to Merocyanine in Aqueous Media and Its Application to Colorimetric Temperature Indication2010

    • Author(s)
      Yasuhiro Shiraishi, Masataka Itoh, Takayuki Hirai
    • Journal Title

      Physical Chemistry Chemical Physics 12

      Pages: 13737-13745

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fluorescence Properties of Polyamines Bearing Two Terminal Quinoline Fragments in Water2010

    • Author(s)
      Chizuru Ichimura, Yasuhiro Shiraishi, Takayuki Hirai
    • Journal Title

      Tetrahedron 66

      Pages: 5594-5601

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A Distyryl BODIPY Derivative as a Fluorescent Probe for Selective Detection of Chromium(III)2010

    • Author(s)
      Dongping Wang, Yasuhiro Shiraishi, Takayuki Hirai
    • Journal Title

      Tetrahedron Letters 51

      Pages: 2545-2549

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A Coumarin-Thiourea Conjugate as a Fluorescent Probe for Hg(II) in Aqueous Media with a Broad pH range 2-122010

    • Author(s)
      Yasuhiro Shiraishi, Shigehiro Sumiya, Takayuki Hirai
    • Journal Title

      Organic & Biomolecular Chemistry 8

      Pages: 1310-1314

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A Distyryl BODIPY Derivative as a Fluorescent Probe for Selective Detection of Chromium(III)2010

    • Author(s)
      Dongping Wang, Ryo Miyamoto, Yasuhiro Shiraishi, Takayuki Hirai
    • Journal Title

      Tetrahedron Letters

      Volume: 51 Pages: 2545-2549

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fluorescence Properties of Polyamines Bearing Two Terminal Quinoline Fragments in Water2010

    • Author(s)
      Chizuru Ichimura, Yasuhiro Shiraishi, Takayuki Hirai
    • Journal Title

      Tetrahedron

      Volume: 66 Pages: 5594-5601

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Thermal Isomerization of Spiropyran to Merocyanine in Aqueous Media and Its Application to Colorimetric Temperature Indication2010

    • Author(s)
      Yasuhiro Shiraishi, Masataka Itoh, Takayuki Hirai
    • Journal Title

      Physical Chemistry Chemical Physics

      Volume: 12 Pages: 13737-13745

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Local Viscosity Analysis of Pluronic Triblock Copolymer Micelle with Cyanine Dyes as a Fluorescent Probe2010

    • Author(s)
      Yasuhiro Shiraishi, Takuya Inoue, Takayuki Hirai
    • Journal Title

      Langmuir

      Volume: 26 Pages: 17505-17512

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Coumarin-Thiourea Conjugate as a Fluorescent Probe for Hg(II) in Aqueous Media with a Broad pH Range 2-122010

    • Author(s)
      Yasuhiro Shiraishi, et al
    • Journal Title

      Organic & Biomolecular Chemistry 8

      Pages: 1310-1314

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] BODIPY-Conjugated Thermoresponsive Copolymer as a Fluorescent Thermometer Based on Polymer Microviscosity2009

    • Author(s)
      Dongping Wang, Ryo Miyamoto, Yasuhiro Shiraishi, Takayuki Hirai
    • Journal Title

      Langmuir 25

      Pages: 13176-13182

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Spiropyran as a Selective, Sensitive, and Reproducible Cyanide Anion Receptor2009

    • Author(s)
      Yasuhiro Shiraishi, Kenichi Adachi, Masataka Itoh, Takayuki Hirai
    • Journal Title

      Organic Letters 11

      Pages: 3482-3485

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of Alkyl Chain Length on Cu(II)-Selective Green Fluorescence of Rhodamine-Diacetic Acid Conjugates2009

    • Author(s)
      Xuan Zhang, Shigehiro Sumiya, Yasuhiro Shiraishi, Takayuki Hirai
    • Journal Title

      Journal of Photochemistry and Photobiology, A : Chemistry 205

      Pages: 215-220

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of Poly-N-Isopropyl acrylamide on Fluorescence Properties of CdS/Cd(OH)2 Nanoparticles in Water2009

    • Author(s)
      Yasuhiro Shiraishi, Kenichi Adachi, Shunsuke Tanaka, Takayuki Hirai
    • Journal Title

      Journal of Photochemistry and Photobiology, A : Chemistry 205

      Pages: 51-59

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A BODIPY-Indole Conjugate as a Colorimetric and Fluorometric Probe for Fluoride Anion Detection2009

    • Author(s)
      Yasuhiro Shiraishi, Hajime Maehara, Takahiro Sugii, Dongping Wang, Takayuki Hirai
    • Journal Title

      Tetrahedron Letters 50

      Pages: 4293-4296

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Indole-Azadiene Conjugate as a Colorimetric and Fluorometric Probe for Selective Fluoride Ion Detection2009

    • Author(s)
      Yasuhiro Shiraishi, Hajime Maehara, Takayuki Hirai
    • Journal Title

      Organic & Biomolecular Chemistry 7

      Pages: 2072-2076

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Spiropyran-Conjugated Thermoresponsive Copolymer as a Colorimetric Thermometer with Linear and Reversible Color Change2009

    • Author(s)
      Yasuhiro Shiraishi, Ryo Miyamoto, Takayuki Hirai
    • Journal Title

      Organic Letters 11

      Pages: 1571-1574

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Spiropyran-Conjugated Thermoresponsive Copolymer as a Colorimetric Thermometer with Linear and Reversible Color Change2009

    • Author(s)
      Yasuhiro Shiraishi, et al.
    • Journal Title

      Organic Letters 11

      Pages: 1571-1574

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Indole-Azadiene Conjugate as a Colorimetric and Fluorometric Probe for Selective Fluoride Ion Detection2009

    • Author(s)
      Yasuhiro Shiraishi, et al.
    • Journal Title

      Organic & Biomolecular Chemistry 7

      Pages: 2072-2076

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A BODIPY-Indole Conjugate as a Colorimetric and Fluorometric Probe for Fluoride Anion Detection2009

    • Author(s)
      Donping Wang, et al.
    • Journal Title

      Tetrahedron Letters 50

      Pages: 4293-4296

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of Poly-N-Isopropylacrylamide on Fluorescence Properties of CdS/Cd(OH)_2 Nanoparticles in Water2009

    • Author(s)
      Yasuhiro Shiraishi, et al.
    • Journal Title

      Journal of Photochemistry and Photobiology A : Chemistry 205

      Pages: 51-59

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of Alkyl Chain Length on Cu(II)-Selective Green Fluorescence of Rhodamine-Diacetic Acid Conjugates2009

    • Author(s)
      Xuan Zhang, et al.
    • Journal Title

      Journal of Photochemistry and Photobiology A : Chemistry 205

      Pages: 215-220

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Spiropyran as a Selective, Sensitive, and Reproducible Cyanide Anion Receptor2009

    • Author(s)
      Yasuhiro Shiraishi, et al.
    • Journal Title

      Organic Letters 11

      Pages: 3482-3485

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] BODIPY-Conjugated Thermoresponsive Copolymer as a Fluorescent Thermometer Based on Polymer Microviscosity2009

    • Author(s)
      Dongping Wang, et al.
    • Journal Title

      Langmuir 25

      Pages: 13176-13182

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] クマリン-スピロピラン複合体による水中シアン化物イオンの選択的蛍光センシング2011

    • Author(s)
      Shigehiro Sumiya, Yasuhiro Shiraishi, Takayuki Hirai
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      神奈川大学
    • Year and Date
      2011-03-28
    • Related Report
      2010 Final Research Report
  • [Presentation] クマリン-スピロピラン複合体による水中シアン化物イオンの選択的蛍光センシング2011

    • Author(s)
      角谷繁宏、白石康浩、平井隆之
    • Organizer
      日本化学会第91回春季大会
    • Place of Presentation
      横浜(神奈川大学)
    • Year and Date
      2011-03-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] スピロピラン-コレステロール複合体のゲル化およびフォトクロミッグ挙動2011

    • Author(s)
      Yasuhori Yoshia, Takuya Inoue, Yasuhiro Shiraishi, Takayuki Hirai
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      神奈川大学
    • Year and Date
      2011-03-27
    • Related Report
      2010 Final Research Report
  • [Presentation] スピロピラン-コレステロール複合体のゲル化およびフォトクロミック挙動2011

    • Author(s)
      吉田靖教、井上拓也、白石康浩, 平井隆之
    • Organizer
      日本化学会第91回春季大会
    • Place of Presentation
      横浜(神奈川大学)
    • Year and Date
      2011-03-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] フルオレセイン-スピロピラン複合体によるシアン化物イオンの発色センシング2011

    • Author(s)
      Takayuki Di, Sigehiro Sumiya, Yasuhiro Shiraishi, Takayuki Hirai
    • Organizer
      日本化学会第91春季年会
    • Place of Presentation
      神奈川大学
    • Year and Date
      2011-03-26
    • Related Report
      2010 Final Research Report
  • [Presentation] フルオレセイン-スピロピラン複合体によるシアン化物イオンの発色センシング2011

    • Author(s)
      道井孝征、角谷繁宏、白石康浩, 平井隆之
    • Organizer
      日本化学会第91回春季大会
    • Place of Presentation
      横浜(神奈川大学)
    • Year and Date
      2011-03-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] クマリン-スピロピラン複合体による水中シアン化物イオンの選択的蛍光センシング2010

    • Author(s)
      Shigehiro Sumiya, Yasuhiro Shiraishi, Takayuki Hirai
    • Organizer
      第29回溶媒抽出討論会
    • Place of Presentation
      広島大学東広島キャンパス
    • Year and Date
      2010-11-26
    • Related Report
      2010 Final Research Report
  • [Presentation] クマリン-スピロピラン複合体による水中シアン化物イオンの選択的蛍光センシング2010

    • Author(s)
      角谷繁宏、白石康浩、平井隆之
    • Organizer
      第29回溶媒抽出討論会
    • Place of Presentation
      東広島(広島大学)
    • Year and Date
      2010-11-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] スピロピラン類の熱異性化における溶媒粘度の効果2010

    • Author(s)
      Takuya Inoue, Yasuhiro Shiraishi, Takayuki Hirai
    • Organizer
      2010年光化学討論会
    • Place of Presentation
      千葉大学西千葉キャンパス
    • Year and Date
      2010-09-09
    • Related Report
      2010 Final Research Report
  • [Presentation] ベンゾキサジアゾール-チオウレア複合体によるHg(II)イオンの選択的蛍光センシング2010

    • Author(s)
      Takahiro Sugii, Shigehiro Sumiya, Yasuhiro Shiraishi, Takayuki Hirai
    • Organizer
      2010年光化学討論会
    • Place of Presentation
      千葉大学西千葉キャンパス
    • Year and Date
      2010-09-09
    • Related Report
      2010 Final Research Report
  • [Presentation] スピロピラン類の熱異性化における溶媒粘度の効果2010

    • Author(s)
      井上拓也、白石康浩、平井隆之
    • Organizer
      2010光化学討論会
    • Place of Presentation
      西千葉(千葉大学)
    • Year and Date
      2010-09-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 二つのニトロ基を有するスピロピラン誘導体を用いたシアン化物イオンによる高感度発色センシング2010

    • Author(s)
      Masataka Itoh, Yasuhiro Shiraishi, Takayuki Hirai
    • Organizer
      2010年光化学討論会
    • Place of Presentation
      千葉大学西千葉キャンパス
    • Year and Date
      2010-09-08
    • Related Report
      2010 Final Research Report
  • [Presentation] クマリン-スピロピラン複合体による水中シアン化物イオンの選択的蛍光センシング2010

    • Author(s)
      Shigehiro Sumiya, Yasuhiro Shiraishi, Takayuki Hirai
    • Organizer
      2010年光化学討論会
    • Place of Presentation
      千葉大学西千葉キャンパス
    • Year and Date
      2010-09-08
    • Related Report
      2010 Final Research Report
  • [Presentation] クマリン-スピロピラン複合体による水中シアン化物イオンの選択的蛍光センシング2010

    • Author(s)
      角谷繁宏、白石康浩、平井隆之
    • Organizer
      2010光化学討論会
    • Place of Presentation
      西千葉(千葉大学)
    • Year and Date
      2010-09-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 二つのニトロ基を有するスピロピラン誘導体を用いたシアン化物イオンによる高感度発色センシング2010

    • Author(s)
      伊藤正隆、白石康浩、平井隆之
    • Organizer
      2010光化学討論会
    • Place of Presentation
      西千葉(千葉大学)
    • Year and Date
      2010-09-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] ベンゾキサジアゾール-チオウレア複合体によるHg(II)イオンの選択的蛍光センシング2010

    • Author(s)
      杉井孝光、角谷繁宏、白石康浩、平井隆之
    • Organizer
      2010光化学討論会
    • Place of Presentation
      西千葉(千葉大学)
    • Year and Date
      2010-09-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 水溶液中におけるスピロピラン類のサーモクロミズム2010

    • Author(s)
      Masataka Itoh, Ryo Miyamoto, Yasuhiro Shiraishi, Takayuki Hirai
    • Organizer
      日本化学会第90春季年会
    • Place of Presentation
      近畿大学東大阪キャンパス
    • Year and Date
      2010-03-29
    • Related Report
      2010 Final Research Report
  • [Presentation] キノリン誘導体によるCu(II)の選択的蛍光センシング2010

    • Author(s)
      Chizuru Ichimura, Yasuhiro Shiraishi, Takayuki Hirai
    • Organizer
      日本化学会第90春季年会
    • Place of Presentation
      近畿大学東大阪キャンパス
    • Year and Date
      2010-03-27
    • Related Report
      2010 Final Research Report
  • [Presentation] BODIPY誘導体によるフッ化物イオンの発色・発光センシング2010

    • Author(s)
      Takahiro Sugii, Hajime Maehara, Yasuhiro Shiraishi, Takayuki Hirai
    • Organizer
      日本化学会第90春季年会
    • Place of Presentation
      近畿大学東大阪キャンパス
    • Year and Date
      2010-03-27
    • Related Report
      2010 Final Research Report
  • [Presentation] クマリン-チオウレア複合体によるHg(II)イオンの選択的発色センシング2009

    • Author(s)
      Shigehiro Sumiya, Yasuhiro Shiraishi, Takayuki Hirai
    • Organizer
      2009年光化学討論会
    • Place of Presentation
      桐生市民文化会館
    • Year and Date
      2009-09-17
    • Related Report
      2010 Final Research Report
  • [Presentation] クマリンーチオウレア複合体によるHg(II)イオンの選択的蛍光センシング2009

    • Author(s)
      角谷繁宏, ら
    • Organizer
      2009年光化学討論会
    • Place of Presentation
      桐生(桐生市民文化会館)
    • Year and Date
      2009-09-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] スピロピランをプローブ分子とするシアン化物イオンの高感度発色センシング2009

    • Author(s)
      Yasuhiro Shiraishi, Masataka Itoh, Kenichi Adachi, Takayuki Hirai
    • Organizer
      2009年光化学討論会
    • Place of Presentation
      桐生市民文化会館
    • Year and Date
      2009-09-16
    • Related Report
      2010 Final Research Report
  • [Presentation] スピロピランをプローブ分子とするシアン化物イオンの高感度発色センシング2009

    • Author(s)
      白石康浩, ら
    • Organizer
      2009年光化学討論会
    • Place of Presentation
      桐生(桐生市民文化会館)
    • Year and Date
      2009-09-16
    • Related Report
      2009 Annual Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report
  • [Patent(Industrial Property Rights)] シアン化物イオンを蛍光により検出するためのキット2010

    • Inventor(s)
      白石康浩
    • Industrial Property Rights Holder
      大阪大学
    • Industrial Property Number
      2010-137589
    • Filing Date
      2010-06-16
    • Related Report
      2010 Annual Research Report 2010 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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