| Project/Area Number |
21760632
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | Hokkaido University |
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Principal Investigator |
SATOH Yasuharu Hokkaido University, 大学院・工学研究院, 助教 (30360928)
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| Research Collaborator |
TAJIMA Kenji 北海道大学, 大学院・工学研究院, 准教授 (00271643)
HAN Xuerong 北海道大学, 大学院・工学研究院, 博士後期課程
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 酵素反応 / 環境材料 / バイオテクノロジー / バイオリアクター |
|---|
| Research Abstract |
Polyhydroxyalkanoates (PHAs), which originate from renewable resources such as sugars and vegetable oils, have attracted great interest as alternatives to petrochemical-based plastics. To construct a novel cell-free PHA production system from sugars as feedstocks, an (R)-specific and NADH-dependent reductase is needed. In this study, we successfully developed the reductases to exchange stereo-selectivity of an (S)-specific enzyme. In addition, we could find the reductase from databases.
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