Analysis of insulin-regulated mechanism affecting feeding behavior
| Project/Area Number |
21770081
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Animal physiology/Animal behavior
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| Research Institution | Tokushima Bunri University |
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Principal Investigator |
SADAMOTO Hisayo Tokushima Bunri University, 香川薬学部, 助教 (70374220)
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| Co-Investigator(Renkei-kenkyūsha) |
AONUMA Hitoshi 徳島文理大学 (20333643)
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| Research Collaborator |
HAMA Noriyuki 島根大学, 医学部, 助教
KOBAYASHI Suguru 徳島文理大学, 香川薬学部, 助教
MURKAMI Jyun 徳島文理大学, 香川薬学部, 博士研究員
ITO Etsuro 徳島文理大学, 香川薬学部, 教授
FUJITO Yutaka 札幌医科大学, 医学部, 準教授
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 行動学 / 神経化学 / 脳・神経 / 分子生物学 / 体液性調節 |
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| Research Abstract |
In the pond snail Lymnaea stagnalis, the neural circuitry underlying feeding is well described. I here studied the insulin-regulated mechanism affecting feeding behavior in the central nervous system (CNS) of Lymnaea. First, I examined the gene expression of molluscan insulin-related peptide II(MIPII) in the CNS. As a result, several days of hunger or satiation did not have effects on gene expression of MIPII. More, the feeding response to sucrose did not correlate to MIPII gene expression. Next, I examined to identify the neurons that respond to insulin or sucrose application to animals. The neurons that respond to those stimuli were in the buccal ganglia that contain the neural circuitry for feeding.
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Report
(3 results)
Research Products
(32 results)
