| Budget Amount *help |
¥6,634,745 (Direct Cost: ¥5,103,650、Indirect Cost: ¥1,531,095)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2010: ¥2,084,745 (Direct Cost: ¥1,603,650、Indirect Cost: ¥481,095)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Research Abstract |
Although it is reported that lysophosphatidylserine(LysoPS)has various cellular activities in vitro, very little is known about its presence, synthetic enzyme, receptor and patho-physiological roles. In this study, we showed that LysoPS is produced at inflamed sites in mice and PS-PLA1 is involved in its production. LysoPS was also found to suppress concanavalin A-induced hepatic injury in mice.
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