Structural studies of the regulatory factor of a functional RNA, steroid hormone RNA activator.
| Project/Area Number |
21770120
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Structural biochemistry
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| Research Institution | Tokyo Metropolitan University |
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Principal Investigator |
MISHIMA Masaki Tokyo Metropolitan University, 理工学研究科, 准教授 (70346310)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 立体構造解析 / 生体高分子 / タンパク質 / 発現制御 / NMR / 分子 / 蛋白質 / 生体分子 |
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| Research Abstract |
For the purpose of understanding the mechanism of transcriptional repression, we have determined three dimensional structure of the complex of SHARP-SPOC domain/SMRT peptide using heteronuclear NMR. As a result, we have established that the molecular recognition of its complex.
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Report
(3 results)
Research Products
(11 results)
