Functional analysis of heparan sulfate fine structures in Drosophila axon guidance
| Project/Area Number |
21770154
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Functional biochemistry
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| Research Institution | 財団法人東京都医学総合研究所 (2011)
Tokyo Metropolitan Organization for Medical Research (2009-2010) |
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Principal Investigator |
KAMIMURA Keisuke 財団法人東京都医学総合研究所, 脳発達・神経再生研究分野, 主席研究員 (30529524)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | ヘパラン硫酸プロテオグリカン / ショウジョウバエ / ヘパラン硫酸 / プロテオグリカン / シナプス形成 / Wnt / ショウジョウバェ |
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| Research Abstract |
We have established the "glyocogenetics" approach, which allow the manipulation of heparan sulfate fine structures at will, using Drosophila, for which sophisticated genetic techniques are available. We also found that HSPGs have important roles in synapse formation.
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Report
(4 results)
Research Products
(23 results)
