| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
|---|
| Research Abstract |
In this study, the translation regulation was investigated by the quantitative imaging of endogenous mRNA and protein in living cells. By quantifying GFP mRNA and its corresponding protein, GFP in the same cell, I observed a considerable cell-to-cell variation in translation activity. Furthermore, the mRNA dynamics analyzed in stressed cells indicated that the translation repression was maintained by harboring endogenous mRNA in stress-induced granules.
|
