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Analysis of hierarchical structure of proteins network

Research Project

Project/Area Number 21770174
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Biophysics
Research InstitutionNara Institute of Science and Technology

Principal Investigator

KAMIKUBO Hironari  Nara Institute of Science and Technology, 物質創成科学研究科, 准教授 (20311128)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
KeywordsX線溶液散乱 / クラスリン被覆小胞輸送 / マルチドメイン蛋白質 / ドメイン再配置 / ドメイン配置構造
Research Abstract

Concerning signal transduction and intracellular vesicular traffic, multi-domain proteins comprised of several functional domains act a central role in the biological functions. In this work, to elucidate the molecular mechanism of the hierarchical regulation involving multi-domain proteins, domain rearrangement of multi-domain proteins initiated by stimulating each domain, and intermolecular and intermolecular regulation associated with the domain rearrangement were examined by using x-ray scattering and dynamic light scattering. In the results, the multi-domain proteins of GGA involved in vesicular traffic and Ppr in a two component regulatory system exhibit intermolecular dissociation and association of their domains during their function expression, and the domain rearrangements are expected to regulate molecular events of protein ensembles involving the multi-domain proteins.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (113 results)

All 2011 2010 2009 Other

All Journal Article (19 results) (of which Peer Reviewed: 11 results) Presentation (87 results) Book (5 results) Remarks (2 results)

  • [Journal Article] Systematic alanine insertion reveals the essential regions that encode structure formation and activity of dihydrofolate reductas.2011

    • Author(s)
      Shiba R., Umeyama M., Tsukasa S., Kamikubo H., Yamazaki Y., Yamaguchi M., Iwakura M., Kataoka M.
    • Journal Title

      BIOPHYSICS 7

      Pages: 1-10

    • Related Report
      2010 Final Research Report
  • [Journal Article] Size-controlled aggregation of cube-shaped EuS nanocrystals with magneto-optic properties in solution.2011

    • Author(s)
      Tanaka A., Kamikubo H., Kataoka M., Hasegawa Y., Kawai T.
    • Journal Title

      Langmuir 27

      Pages: 104-108

    • Related Report
      2010 Final Research Report
  • [Journal Article] Systematic alanine insertion reveals the essential regions that encode structure formation and activity of dihydrofolate reductase2011

    • Author(s)
      Rumi Shiba
    • Journal Title

      BIOPHYSICS

      Volume: 7 Pages: 1-10

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] フォトアクティブイェロープロテインの中性子結晶構造解析2010

    • Author(s)
      上久保裕生、山口繁生、片岡幹雄
    • Journal Title

      RADIOISOTOPES 59

      Pages: 289-297

    • NAID

      10026244827

    • Related Report
      2010 Final Research Report
  • [Journal Article] Cytochrome c polymerization by successive domain swapping at the C-terminal helix.2010

    • Author(s)
      Hirota S., Hattori Y., Nagao S., Taketa M., Komori H., Kamikubo H., Wang Z., Takahashi I., Negi S., Sugiura Y., Kataoka M., Higuchi Y.
    • Journal Title

      Proc. Natl. Acad. Sci. USA. 107

      Pages: 12854-12859

    • NAID

      120005716875

    • Related Report
      2010 Final Research Report
  • [Journal Article] Self-assembling Formation and Enhanced Magnetic Properties of Three-dimensional Super-lattice Structures Composed of Cube- and Sphere-shaped EuS nanocrsytals.2010

    • Author(s)
      Tanaka A., Kamikubo H., Doi Y., Hinatsu Y., Kataoka M., Kawai T., Hasegawa Y.
    • Journal Title

      Chemistry of Materials 22

      Pages: 1776-1781

    • Related Report
      2010 Final Research Report
  • [Journal Article] Non-local interaction responsible for the tertiary structural formation of Staphylococcal nuclease.2010

    • Author(s)
      Kato S., Kamikubo H., Hirano S., Yamazaki Y., Kataoka M.
    • Journal Title

      Biophys. J. 98

      Pages: 678-786

    • Related Report
      2010 Final Research Report
  • [Journal Article] Effect of conformational states on protein dynamical transition2010

    • Author(s)
      Hiroshi Nakagawa
    • Journal Title

      Biochim.Biophys.Acta

      Volume: 1804 Pages: 27-33

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Non-local interaction responsible for the tertiary structural formation of Staphylococcal nuclease2010

    • Author(s)
      Shingo Kato
    • Journal Title

      Biophys.J.

      Volume: 98 Pages: 678-786

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Self-Assembly and Enhanced Magnetic Properties of Three-dimensional Superlattice Structures Composed of Cube- and Sphere-Shaped EuS Nanocrsytals2010

    • Author(s)
      Atsushi Tanaka
    • Journal Title

      Chem.Mat.

      Volume: 22 Pages: 1776-1781

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cytochrome c polymerization by successive domain swapping at the C-terminal helix2010

    • Author(s)
      Shun Hirota
    • Journal Title

      Proc.Natl.Acad.Sci.USA

      Volume: 107 Pages: 12854-12859

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Size-controlled aggregation of cube-shaped EuS nanocrystals with magneto-optic properties in solution2010

    • Author(s)
      Atsushi Tanaka
    • Journal Title

      Langmuir

      Volume: 27 Pages: 104-108

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] フォトアクティブイェロープロテインの中性子結晶構造解析2010

    • Author(s)
      上久保裕生
    • Journal Title

      RADIOISOTOPES

      Volume: 59 Pages: 289-297

    • NAID

      10026244827

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Non-local interaction responsible for the tertiary structural formation of Staphylococcal nuclease.2010

    • Author(s)
      S.Kato, H.Kamikubo, S.Hirano, Y.Yamazaki, M.Kataoka
    • Journal Title

      Biophys.J. 98

      Pages: 678-786

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of conformational states on protein dynamical transition.2010

    • Author(s)
      H.Nakagawa, H.Kamikubo, M.Kataoka
    • Journal Title

      Biochim.Biophys.Acta 1804

      Pages: 27-33

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Self-assembling Formation and Enhanced Magnetic Properties of Three-dimensional Super-lattice Structures Composed of Cube-and Sphere-shaped EuS nanocrsytals2010

    • Author(s)
      Atsushi Tanaka
    • Journal Title

      Chemistry of Materials (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of conformational states on protein dynamical transition.2009

    • Author(s)
      Nakagawa H., Kamikubo H., Kataoka M.
    • Journal Title

      Biochim Biophys Acta. 1804

      Pages: 27-33

    • Related Report
      2010 Final Research Report
  • [Journal Article] Self-aggregation of magnetic semiconductor EuS nanocrystals.2009

    • Author(s)
      Tanaka A., Hasegawa Y., Kamikubo H., Kataoka M., Kawai T.
    • Journal Title

      THIN SOLID FILMS 518

      Pages: 870-872

    • Related Report
      2010 Final Research Report
  • [Journal Article] Self-aggregation of magnetic semiconductor EuS nanocrystals.2009

    • Author(s)
      A.Tanaka, Y.Hasegawa, H.Kamikubo, M.Kataoka, T.Kawai
    • Journal Title

      Thin Solid Films 518

      Pages: 870-872

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Fluctuation controls enzymatic activity of Staphylococcal nuclease2010

    • Author(s)
      Hironari Kamikubo, et al.
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津
    • Year and Date
      2010-12-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] Classification of the functional element of dihydrofolate reductase by the systematic alanine insertion2010

    • Author(s)
      Rumi Shiba, et al.
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津
    • Year and Date
      2010-12-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] FRET analysis of structural changes in staphylococcal nuclease2010

    • Author(s)
      Yusuke Kishi, et al.
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津
    • Year and Date
      2010-12-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] Cytochrome c polymerization by successive domain swapping at the C-terminal helix2010

    • Author(s)
      Zhonghua Wang, et al.
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津
    • Year and Date
      2010-12-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] The investigation of the relationship between non-local interaction and the effect of single alanine insertion in staphylococcal nuclease2010

    • Author(s)
      Hiroki Sawada, et al.
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津
    • Year and Date
      2010-11-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] Measurements of loop formation in the denatured state of staphylococcal nuclease2010

    • Author(s)
      Mariko Yamaguchi, et al.
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津
    • Year and Date
      2010-11-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] Cytochrome c polymerization by successive domain swapping at the C-terminal helix2010

    • Author(s)
      Shun Hirota, et al.
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] A case of EspB from enterohaemorrhagic Escherichia coli2010

    • Author(s)
      Daizo Hamada, et al.
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] Property of a structural element of SNase-like domain in human p1002010

    • Author(s)
      Yoko Ogawa, et al.
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] The investigation of the relationship between non-local interaction and the effect of single alanine insertion in staphylococcal nuclease2010

    • Author(s)
      Hiroki Sawada, et al.
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] FRET analysis of structural changes in Staphylococcal nuclease2010

    • Author(s)
      Yusuke Kishi, et al.
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] Solution structure of the light sensor histidine kinase of Ppr comprised of the PYP and Bph domains2010

    • Author(s)
      Junko Miura, et al.
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Solution structural analysis of Drosophila GGA2010

    • Author(s)
      Maiko Naruse, et al.
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Analysis of solution state of the interaction protein of Rc-PYP2010

    • Author(s)
      Miki Hayashi, et al.
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] The role of each residue in the flexible Ω loop of Staphylococcal nuclease on the catalytic activity2010

    • Author(s)
      Changjun Ahn, et al.
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Classification of the functional element of dihydrofolate reductase (DHFR) by the systemic alanine insertion2010

    • Author(s)
      Rumi Shiba, et al.
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Synthesis of an artificial enzyme by implanting the functional elements of SNase2010

    • Author(s)
      Hironari Kamikubo, et al.
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Urea denaturation of staphylococcal nuclease monitored by tryptophan-cysteine distance2010

    • Author(s)
      Mariko Yamaguchi, et al.
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Substitution effects of basic residues in the photoactive yellow protein of Rhodobacter caplsulatus2010

    • Author(s)
      Yoichi Yamazaki, et al.
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Photoactive Yellow Proteinにおける発色団の機能変調2010

    • Author(s)
      山崎洋一, et al.
    • Organizer
      第16回日本光生物学協会年会
    • Place of Presentation
      吹田
    • Year and Date
      2010-08-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] The effect of alanine insertion mutation for folding process.2010

    • Author(s)
      Hiroki Sawada, et al.
    • Organizer
      The 4th Shanghai International Conference on Biophysics and Molecular Biology
    • Place of Presentation
      Shanghai-Jiashan, China
    • Year and Date
      2010-08-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] Extraction of the regions encoded foldability and/or functionability from dihydrofolate reductase by the systematic alanine insertion2010

    • Author(s)
      Rumi Shiba, et al.
    • Organizer
      The 4th Shanghai International Conference on Biophysics and Molecular Biology
    • Place of Presentation
      Shanghai-Jiashan, China
    • Year and Date
      2010-08-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 精子由来蛋白質IZUMO,その構造と受精膜融合での役割2010

    • Author(s)
      萩原義久, 井上直和, 浜田大三, 上久保裕生, 平田邦生, 片岡幹雄, 山本雅貴, 伊川正人, 岡部勝
    • Organizer
      日本蛋白質科学会年会
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-18
    • Related Report
      2010 Final Research Report
  • [Presentation] 網羅的アラニン挿入変異解析法を用いたジヒドロ葉酸還元酵素の機能発現及び構造形成領域の抽出2010

    • Author(s)
      芝るみ, 上久保裕生, 梅山美香, 政さやか, 山口真理子, 山崎洋一, 巌倉正寛, 片岡幹雄
    • Organizer
      日本蛋白質科学会年会
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-18
    • Related Report
      2010 Final Research Report
  • [Presentation] 精子由来蛋白質IZUMO,その構造と受精膜融合での役割2010

    • Author(s)
      萩原義久, et al.
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] 網羅的アラニン挿入変異解析法を用いたジヒドロ葉酸還元酵素の機能発現及び構造形成領域の抽出2010

    • Author(s)
      芝るみ, et al.
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] 中性子結晶構造解析による蛋白質分子内プロトン移動機構の解明2010

    • Author(s)
      上久保裕生
    • Organizer
      生命物質構造解析研究会
    • Place of Presentation
      東海村
    • Year and Date
      2010-03-25
    • Related Report
      2010 Final Research Report
  • [Presentation] 中性子結晶構造解析による蛋白質分子内プロトン移動機構の解明2010

    • Author(s)
      上久保裕生
    • Organizer
      茨城県中性子利用促進研究会
    • Place of Presentation
      リコッティ
    • Year and Date
      2010-03-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] 分子内プロトン移動:Photoactive Yellow Proteinの水素結合構造から何がわかるのか2010

    • Author(s)
      上久保裕生、山口繁雄、片岡幹雄
    • Organizer
      分子研研究会 広がるロドプシンの仲間から何がわかるのか、何をもたらすのか
    • Place of Presentation
      岡崎コンファレンスセンター
    • Year and Date
      2010-03-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Fluctuation controls enzymatic activity of Staphylococcal nuclease.2010

    • Author(s)
      H.Kamikubo(他2名)
    • Organizer
      The 4th International Symposium "Molecuar Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      Otsu, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] Classification of the functional element of dihydrofolate reductase by the systematic alanine insertion.2010

    • Author(s)
      R.Shiba, H.Kamikubo, M.Umeyama, S.Tsukasa, M.Yamaguchi, Y.Yamazaki, M.Iwakura, M.Kataoka.
    • Organizer
      The 4th International Symposium "Molecuar Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      Otsu, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] FRET analysis of structural changes in staphylococcal nuclease2010

    • Author(s)
      Y.Kishi, T.Muto, M.Yamaguchi, I.Iijima, Y.Yamazaki, H.Kamikubo, T.Hohsaka, M.Kataoka.
    • Organizer
      The 4th International Symposium "Molecuar Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      Otsu, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] Cytochrome c polymerization by successive domain swapping at the C-terminal helix.2010

    • Author(s)
      Z.Wang, Y.Hattori, S.Nagao, M.Takeda, H.Komori, H.Kamikubo, I.Takahashi, S.Negi, Y.Sugiura, M.Kataoka, Y.Higuchi, S.Hirota.
    • Organizer
      The 4th International Symposium "Molecuar Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      Otsu, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] Measurements of loop formation in the denatured state of staphylococcal nuclease.2010

    • Author(s)
      M.Yamaguchi, Y.Yamazaki, H.Kamikubo, M.Kataoka.
    • Organizer
      The 4th International Symposium "Molecuar Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      Otsu, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] The investigation of the relationship between non-local interaction and the effect of single alanine insertion in staphylococcal nuclease.2010

    • Author(s)
      H.Sawada, H.Kamikubo, Y.Yamazaki, M.Kataoka.
    • Organizer
      The 4th International Symposium "Molecuar Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      Otsu, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] Cytochrome c polymerization by successive domain swapping at the C-terminal helix.2010

    • Author(s)
      S.Hirota, Y.Hattori, S.Nagao, M.Takeda, H.i Komori, H.Kamikubo(他6名)
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      仙台
    • Related Report
      2010 Final Research Report
  • [Presentation] Intrinsically less-ordered bacterial effectors : A case of EspB from enterohaemorrhagic Escherichia coli.2010

    • Author(s)
      D.Hamada, H.Kamikubo(他2名)
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      仙台
    • Related Report
      2010 Final Research Report
  • [Presentation] Property of a structural element of SNase-like domain in human p100.2010

    • Author(s)
      Y.Ogawa, H.Kamikubo.(他4名)
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      仙台
    • Related Report
      2010 Final Research Report
  • [Presentation] The investigation of the relationship between non-local interaction and the effect of single alanine insertion in staphylococcal nuclease.2010

    • Author(s)
      H.Sawada, H.Kamikubo, Y.Yamazaki, M.Yamaguchi, M.Kataoka.
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      仙台
    • Related Report
      2010 Final Research Report
  • [Presentation] FRET analysis of structural changes in Staphylococcal nuclease.2010

    • Author(s)
      Y.Kishi, M.Yamaguchi, I.Iijima, Y.Yamazaki, H.Kamikubo(他2名)
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      仙台
    • Related Report
      2010 Final Research Report
  • [Presentation] The role of each residue in the flexible rambda loop of Staphylococcal nuclease on the catalytic activity.2010

    • Author(s)
      C.Ahn, H.Kamikubo, H.i Yoshioka, Y.Yamazaki, M.Yamaguchi, M.Kataoka.
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      仙台
    • Related Report
      2010 Final Research Report
  • [Presentation] Solution structure of the light sensor histidine kinase of Ppr comprised of the PYP and Bph domains.2010

    • Author(s)
      J.Miura, H.Kamikuno, Y.Yamzaki, M.Yamaguchi, M.Kataoka.
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      仙台
    • Related Report
      2010 Final Research Report
  • [Presentation] Solution structural analysis of Drosophila GGA.2010

    • Author(s)
      M.Naruse, H. Kamikubo(他6名)
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      仙台
    • Related Report
      2010 Final Research Report
  • [Presentation] Analysis of solution state of the interaction protein of Rc-PYP.2010

    • Author(s)
      M.Hayashi, Y.Yamazaki, H.Kamikubo, M.Kataoka.
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      仙台
    • Related Report
      2010 Final Research Report
  • [Presentation] Classification of the functional element of dihydrofolate reductase (DHFR) by the systemic alanine insertion.2010

    • Author(s)
      R.Shiba, H.Kamikubo(他6名)
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      仙台
    • Related Report
      2010 Final Research Report
  • [Presentation] Synthesis of an artificial enzyme by implanting the functional elements of SNase.2010

    • Author(s)
      H.Kamikubo, A.Kogasaka, C.Komeda, Y.Yamazaki, M.Yamaguchi, M.Kataoka.
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      仙台
    • Related Report
      2010 Final Research Report
  • [Presentation] Urea denaturation of staphylococcal nuclease monitored by tryptophan-cysteined distance.2010

    • Author(s)
      M.Yamaguchi, Y.Yamazaki, H.Kamikubo, M.Kataoka.
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      仙台
    • Related Report
      2010 Final Research Report
  • [Presentation] Substitution effects of basic residues in the photoactive yellow protein of Rhodobacter caplsolatus.2010

    • Author(s)
      Y.Yamazaki, H.Kamikubo, M.Kataoka.
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      仙台
    • Related Report
      2010 Final Research Report
  • [Presentation] Photoactive Yellow Proteinにおける発色団の機能変調2010

    • Author(s)
      山崎洋一, 上久保裕生, 片岡幹雄
    • Organizer
      日本光生物学協会年会
    • Place of Presentation
      大阪
    • Related Report
      2010 Final Research Report
  • [Presentation] The effect of alanine insertion mutation for folding process2010

    • Author(s)
      H.Sawada, H.Kamikubo, Y.Yamazaki, M.Kataoka.
    • Organizer
      The 4th Shangai International Conference on Biophysics and Molecolar Biology
    • Place of Presentation
      Shanghai-Jiashan, China
    • Related Report
      2010 Final Research Report
  • [Presentation] Extraction of the regions encoded foldability and/or functionability from dihydrofolate reductase by the systematic alanine insertion2010

    • Author(s)
      R.Shiba, H. Kamikubo(他6名)
    • Organizer
      The 4th Shangai International Conference on Biophysics and Molecolar Biology
    • Place of Presentation
      Shanghai-Jiashan, China
    • Related Report
      2010 Final Research Report
  • [Presentation] 分子内プロトン移動: Photoactive Yellow Proteinの水素結合構造から何がわかるのか2010

    • Author(s)
      上久保裕生
    • Organizer
      分子研研究会「拡がるロドプシンの仲間から"何がわかるか""何をもたらすか"」
    • Place of Presentation
      岡崎
    • Related Report
      2010 Final Research Report
  • [Presentation] Extraction of the regions encoded foldability and/or functionability from dihydrofolate reductase by the systematic alanine insertion.2009

    • Author(s)
      R.Shiba, H.Kamikubo, M.Umeyama, S.Tsukasa, Y.Yamazaki, M.Yamaguchi, M.Iwakura, M.Kataoka.
    • Organizer
      The 3rd International Symposium on "Molecuar Science of Fluctuations toward Biological Functions
    • Place of Presentation
      名古屋大学,名古屋
    • Related Report
      2010 Final Research Report
  • [Presentation] Local structure characterization of staphylococcal nuclease by lifetime measurement of tryptophan triplet state.2009

    • Author(s)
      M.Yamaguchi, Y.Yamazaki, H.Kamikubo, M.Kataoka.
    • Organizer
      The 3rd International Symposium on "Molecuar Science of Fluctuations toward Biological Functions
    • Place of Presentation
      名古屋大学,名古屋
    • Related Report
      2010 Final Research Report
  • [Presentation] The properties required for the binding before folding mechanism of the intrinsically disordered mutants of staphylococcal nuclease.2009

    • Author(s)
      M.Onitsuka, H.Kamikubo, Y.Yamazaki, M.Kataoka.
    • Organizer
      The 3rd International Symposium on "Molecuar Science of Fluctuations toward Biological Functions
    • Place of Presentation
      名古屋大学,名古屋
    • Related Report
      2010 Final Research Report
  • [Presentation] Structural characterization of the intrinsically disordered mutants of staphylococcal nuclease by electron paramagnetic resonance spectroscopy2009

    • Author(s)
      H.Sawada, S.M.Budamagunta, H.Kamikubo, Y.Yamazaki, M.Yamaguchi, C.J.Voss, M.Kataoka.
    • Organizer
      The 3rd International Symposium on "Molecuar Science of Fluctuations toward Biological Functions
    • Place of Presentation
      名古屋大学,名古屋
    • Related Report
      2010 Final Research Report
  • [Presentation] Extraction of the structural element of SNase-like domain in human p100 by alanine insertion analysis2009

    • Author(s)
      Y.Ogawa, H.Kamikubo(他4名)
    • Organizer
      The 3rd International Symposium on "Molecuar Science of Fluctuations toward Biological Functions
    • Place of Presentation
      名古屋大学,名古屋
    • Related Report
      2010 Final Research Report
  • [Presentation] 中性子結晶構造解析による蛋白質中の低障壁水素結合の発見2009

    • Author(s)
      上久保裕生
    • Organizer
      日本中性子科学会年会
    • Place of Presentation
      東海村
    • Related Report
      2010 Final Research Report
  • [Presentation] Low barrier hydrogen bond in photoactive yellow protein and its role in photoreaction2009

    • Author(s)
      S.Yamaguchi, H.Kamikubo, M.Kataoka.
    • Organizer
      The 1st NCTU-NAIST Workshop on "Molecolar/Nano Science"
    • Place of Presentation
      Taiwan
    • Related Report
      2010 Final Research Report
  • [Presentation] Structural characterization of the intrinsically disordered mutants of staphylococcal nuclease by electron paramagnetic resonance spectroscopy.2009

    • Author(s)
      H Sawada, M.S.Budamagunta, H.Kamikubo, Y.Yamazaki, M.Yamaguchi, J.C.Voss, M.Kataoka.
    • Organizer
      The 1st NCTU-NAIST Workshop on "Molecolar/Nano Science"
    • Place of Presentation
      Taiwan
    • Related Report
      2010 Final Research Report
  • [Presentation] Crystallographic study of the alanine insertion mutants of Staphylococcal nuclease2009

    • Author(s)
      H.Yoshioka, S.Yamaguchi, H.Kamikubo, Y.Yamazaki, M.Yamaguchi, M.Kataoka.
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2010 Final Research Report
  • [Presentation] Attempt to create an artificial functional protein by exchange of functional elements2009

    • Author(s)
      A.Kogasaka, H.Kamikubo, M.Onitsuka, Y.Yamazaki, M.Yamaguchi, M.Kataoka.
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2010 Final Research Report
  • [Presentation] Direct structural modolation of the structure element of SNase by using the azobenzene linkage2009

    • Author(s)
      K.Saito, H.Kamikubo, Y.Yamazaki, M.Yamaguchi, M.Kataoka.
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2010 Final Research Report
  • [Presentation] ・-value analysis of induced folding : The role of the ligand binding in induced folding of disordered staphylococcal nuclease mutant2009

    • Author(s)
      M.Onitsuka, H.Kamikubo, Y.Yamazaki, M.Kataoka.
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2010 Final Research Report
  • [Presentation] Structural characterization of the intrinsically disordered mutants of staphylococcal nuclease by electron paramagnetic resonance spectroscopy2009

    • Author(s)
      H.Sawada, S.M.Budamagunta, H.Kamikubo, Y.Yamazaki, M.Yamaguchi, C.J.Voss, M.Kataoka.
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2010 Final Research Report
  • [Presentation] Extraction of the regions encoded foldability and/or functionability from dihydrofolate reductase by the systematic alanine insertion2009

    • Author(s)
      R.Shiba, H.Kamikubo, M.Umeyama, S.Tsukasa, Y.Yamazaki, M.Yamaguchi, M.Iwakura, M.Kataoka,
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2010 Final Research Report
  • [Presentation] Extraction of the structural element of SNase-like domain in human p100 by alanine insertion analysis2009

    • Author(s)
      Y.Ogawa, H.Kamikubo(他4名)
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2010 Final Research Report
  • [Presentation] Interaction mechanism of the photoactive yellow protein of Rhodobacter caplsolatus2009

    • Author(s)
      Y.Yamazaki, N.Ota, H.Kamikubo, M.Kataoka.
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2010 Final Research Report
  • [Presentation] The low-temperature spectroscopy of Rc-PYP2009

    • Author(s)
      Y.Hamaguchi, Y.Yamazaki, H.Kamikubo, M.Kataoka.
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2010 Final Research Report
  • [Presentation] Analysis of the different properties in two PYPs by use of chimera proteins2009

    • Author(s)
      K.Matsumoto, Y.Yamazaki, H.Kamikubo, M.Kataoka.
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2010 Final Research Report
  • [Presentation] Low-barrier hydrogen bond in photoactive yellow protein2009

    • Author(s)
      S.Yamaguchi, H.Kamikubo(他4名)
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2010 Final Research Report
  • [Presentation] Light dependent enzyme activity control by use of interaction of the Rc-PYP2009

    • Author(s)
      H.Kubo, Y.Yamazaki, H.Kamikubo, M.Kataoka.
    • Organizer
      日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2010 Final Research Report
  • [Presentation] イェロープロテインの低障壁水素結合の形成とその役割2009

    • Author(s)
      片岡幹雄、上久保裕生、山口繁生
    • Organizer
      生体分子科学討論会
    • Place of Presentation
      北海道大学,札幌
    • Related Report
      2010 Final Research Report
  • [Presentation] 中性子結晶構造解析による蛋白質中の「低障壁」水素結合の発見2009

    • Author(s)
      上久保裕生
    • Organizer
      第9回日本中性子科学会年会
    • Place of Presentation
      茨城
    • Related Report
      2009 Annual Research Report
  • [Presentation] イェロープロテインの低障壁水素結合の形成とその役割2009

    • Author(s)
      片岡幹雄、上久保裕生、山口繁生
    • Organizer
      第36回生体分子化学討論会
    • Place of Presentation
      札幌
    • Related Report
      2009 Annual Research Report
  • [Presentation] Rc-PYPと相互作用タンパク質を用いた酵素活性の光制御系の作製2009

    • Author(s)
      久保晴政
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] Rhodobacter capsulatus由来PYPの相互作用様式の解析2009

    • Author(s)
      山崎洋一
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] Rc-PYPの低温分光2009

    • Author(s)
      濱祐口也
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] キメラを用いたPhotoactive Yellow Proteinの研究2009

    • Author(s)
      松本啓佑
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] Staphylococcal nucleaseアラニン挿入変異体の結晶学的研究2009

    • Author(s)
      吉岡紘志
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] エレメント置換による蛋白質の機能獲得の試み2009

    • Author(s)
      小賀坂彰浩
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] アゾベンゼンを用いた構造エレメントのモジュレーション2009

    • Author(s)
      齊藤謙介
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] 誘導折り畳み反応のΦ値解析:スタフィロコッカルヌクレアーゼ変異体の誘導折り畳み反応におけるリガンド結合の役割2009

    • Author(s)
      鬼塚正義
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] 電子常磁性共鳴分光法による天然変性Staphylococcal nuclease変異体の構造解析2009

    • Author(s)
      澤田宏起
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] 網羅的アラニン挿入変異解析法を用いたジヒドロ葉酸還元酵素の機能発現および構造形成領域の抽出2009

    • Author(s)
      芝るみ
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] 網羅的アラニン挿入変異解析によるHuman p100 SNase様ドメインの構造形成に関わる領域の抽出2009

    • Author(s)
      小川洋子
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] Low barrier hydrogen bond in photoactive yellow protein and its role in photoreaction2009

    • Author(s)
      S.Yamaguchi, H.Kamikubo, M.Kataoka
    • Organizer
      The 1st NCTU-NAIST workshop on "Molecular/Nano Science"
    • Place of Presentation
      新竹(台湾)
    • Related Report
      2009 Annual Research Report
  • [Book] 入門構造生物学(編集:加藤龍一)(2章3節分担)2010

    • Author(s)
      上久保裕生
    • Publisher
      共立出版
    • Related Report
      2010 Final Research Report
  • [Book] 入門 構造生物学(編集:加藤龍一 2章3節X線溶液散乱)2010

    • Author(s)
      上久保裕生
    • Total Pages
      8
    • Publisher
      共立出版
    • Related Report
      2010 Annual Research Report
  • [Book] 中性子回折の基礎と応用(応用11)(フォトアクティブイェロープロテインの中性子結晶構造解析)2010

    • Author(s)
      上久保裕生、山口繁生、片岡幹雄
    • Total Pages
      9
    • Publisher
      日本アイソトープ協会RADIOISOTOPES
    • Related Report
      2009 Annual Research Report
  • [Book] Springer Structure of the photointermediate of photoactive yellow protein and the propagataion mechanism of structural change.(eds. by K.Kuwajima, Y.Goto, F.Hirata, M.Kataoka, M.Terazima)2009

    • Author(s)
      M.Kataoka, H.Kamikubo.
    • Publisher
      Water and Biomolecules
    • Related Report
      2010 Final Research Report
  • [Book] Water and Biomolecules(eds.by K.Kuwajima, Y.Goto, F.Hirata, M.Kataoka and M.Terazima, Structure of the photointermediate of photoactive yellow protein and the propagataion mechanism of structural change.)2009

    • Author(s)
      M.Kataoka, H.Kamikubo
    • Total Pages
      12
    • Related Report
      2009 Annual Research Report
  • [Remarks] ホームページ等

    • URL

      http://mswebs.naist.jp/LABs/kataoka/index.html

    • Related Report
      2010 Final Research Report
  • [Remarks]

    • URL

      https://sites.google.com/site/kmkbhp/home

    • Related Report
      2010 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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