Molecular organization of tricellular junction
| Project/Area Number |
21770213
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Cell biology
|
|---|
| Research Institution | Kobe University |
|---|
Principal Investigator |
ODA Yukako Kobe University, 大学院・医学研究科, 助教 (70452498)
|
|---|
| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Keywords | 上皮細胞 / 細胞間接着 / タイトジャンクション / トリセルラージャンクション / 細胞骨格 / アクチン / トリセルラータイトジャンクション / トリセルリン / 細胞接着 |
|---|
| Research Abstract |
In an epithelial layer, each cell forms polygonal structure to establish cell-cell adhesions with neighboring cells. We show that tricelluar junctional protein shapes epithelial cell morphology at the tricelluar corner, which leads to activation of the actin reorganization, thereby shaping the polygonal cell morphology.
|
Report
(3 results)
Research Products
(15 results)
