Microtubles organization regulated by Aurora-A and NDEL1

Research Project

Project/Area Number	21770218
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Cell biology
Research Institution	Nagoya University
Principal Investigator	MORI Daisuke Nagoya University, 医学系研究科, COE特任講師 (00381997)
Project Period (FY)	2009 – 2010
Project Status	Completed (Fiscal Year 2010)
Budget Amount *help	¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000) Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000) Fiscal Year 2009: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Keywords	中心体 / Aurora-Aキナーゼ / NDEL1 / Aurora-A / 微小管 / DRG神経細胞
Research Abstract	We proved the molecular mechanisms which sequencial activation among aPKC, Aurora-A and NDEL1 in neurite elongation. We fistly indicated the common mechanisms in regulating cell cycle, formation of neurite polarity or elongation..