Proteomic analysis of chromatin binding proteins inmouse spermatogoniai stem cells
| Project/Area Number |
21770240
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Developmental biology
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| Research Institution | Kitasato University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 幹細胞 / 精原幹細胞 / 分化 / プロテオーム / レチノイン酸 |
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| Research Abstract |
To reveal differentiation process of spermatogonial stem cells in mice, comparative analysis of nuclear proteome of spermatogonial stem cells and differentiating spermatogonia was performed. None of identified proteins have been characterized with respect to either stem cell self-renewal or spermatogenesis. Future functional studies will clarify the exact roles of these proteins on self-renewal and differentiation of spermatogonial stem cells.
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Report
(4 results)
Research Products
(12 results)
