| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Research Abstract |
To understand morphogenesis at single-cell-level in chordate organogenesis period, ascidian embryo was used in this study. By 3D imaging of ascidian larva, a novel peripheral neuron network structure was found at larval outer tunic. Computer model of the tailbud embryo were made. By 3D-live(4D) imaging of neural tube closure, it was suggested that two independent cell movements accomplish the closure. Thus high-resolution imaging of ascidian embryogenesis enables us to understand how each cell cause morphogenesis of tissue, organ and whole-animal level.
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