| Project/Area Number |
21770243
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Developmental biology
|
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| Research Institution | Gakushuin University (2010)
Tokyo University of Science (2009) |
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Principal Investigator |
OKUMURA Takashi 学習院大学, 理学部, PD 共同研究員 (20449234)
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| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 左右非対称性 / ショウジョウバエ / 非筋定型ミオシンII / 消化管 / 形態形成 / Zipper / 発生生物学 / ミオシンII / 内蔵筋 |
|---|
| Research Abstract |
Many animals exhibit stereotypical left-right (LR) asymmetry in their internal organs. From our genetic analysis, activation of non-muscle myosin II has been suggested to be required for LR asymmetric morphogenesis of the Drosophila embryonic midgut. In this study, we try to ask whether activation of non-muscle myosin II show LR bias in the LR morphogenesis. As a result, we could not clearly confirm its LR-biased activation, but we demonstrated that LR asymmetric cell movement of the midgut depended on non-muscle myosin II activation.
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