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Enhancement of defense response by autophagy modulation, and screening for discovering novel defense activators

Research Project

Project/Area Number 21780041
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Plant pathology
Research InstitutionTokyo University of Science

Principal Investigator

KURUSU Takamitsu  Tokyo University of Science, 総合研究機構, プロジェクト研究員 (50422499)

Research Collaborator KUCHITSU Kazuyuki  東京理科大学, 理工学部, 教授 (50211884)
TAKAHASHI Akira  独立行政法人農業生物資源研究所, 植物科学研究領域耐病性研究ユニット, 研究員 (20414914)
MITSUHARA Ichiro  独立行政法人農業生物資源研究所, 植物科学研究領域植物微生物間相互作用研究ユニット, 研究員 (80370683)
Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords病害抵抗性 / イネ / オートファジー / 細胞内物流 / 自然免疫 / 防疫剤 / 培養細胞 / 耐病性
Research Abstract

Our studies revealed that plant immune responses are regulated by both membrane traffic and degradation system. We established the effective screening methods for novel defense activators by using ROS (reactive oxygen species) monitoring system in tobacco BY-2 cells, and found several candidates of defense activators. We believe that this system is useful for a new pesticide screening for many crops. We also identified several mutants of autophagy genes (Osatgs) in rice.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (19 results)

All 2011 2010 2009 Other

All Journal Article (6 results) (of which Peer Reviewed: 6 results) Presentation (7 results) Book (4 results) Remarks (2 results)

  • [Journal Article] 植物の免疫制御機構~情報素子としてのカルシウムイオンの役割~2011

    • Author(s)
      来須孝光、朽津和幸
    • Journal Title

      理大科学フォーラム 322巻

      Pages: 44-49

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 植物の免疫制御機構~情報素子としてのカルシウムイオンの役割~2011

    • Author(s)
      来須孝光
    • Journal Title

      理大科学フォーラム

      Volume: 322 Pages: 44-49

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Regulation of microbe-associated molecular pattern-induced hypersensitive cell death, phytoalexin production and defense gene expression by calcineurin B-like protein-interacting protein kinases, OsCIPK14/15, in rice cultured cells.2010

    • Author(s)
      来須孝光、濱田淳平、能鹿島央司、北川陽一郎、清塚正弘、高橋章、花俣繁、大野良子、林晃之、岡田憲典、古賀仁一郎、廣近洋彦、山根久和、朽津和幸
    • Journal Title

      Plant Physiology 153巻

      Pages: 678-692

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Roles of calcineurin B-like protein-interacting protein kinases in plant innate immunity in rice.2010

    • Author(s)
      来須孝光、濱田晴康、花俣繁、朽津和幸
    • Journal Title

      Plant Signaling & Behavior. 5巻

      Pages: 1045-1047

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Regulation of microbe-associated molecular pattern-induced hypersensitive cell death, phytoalexin production and defense gene expression by calcineurin B-like protein-interacting protein kinases, OsCIPK14/15, in rice cultured cells2010

    • Author(s)
      来須孝光
    • Journal Title

      Plant Physiology

      Volume: 153 Pages: 678-692

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Roles of calcineurin B-like protein-interacting protein kinases in plant innate immunity in rice2010

    • Author(s)
      来須孝光
    • Journal Title

      Plant Signaling & Behavior

      Volume: 5 Pages: 1045-1047

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 植物の感染防御応答におけるオートファジー動態の解析2011

    • Author(s)
      来須孝光
    • Organizer
      第6回オートファジー研究会
    • Place of Presentation
      ヤマハリゾートつま恋(静岡)
    • Year and Date
      2011-01-13
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] イネ培養細胞の自然免疫応答におけるカルシウム制御型プロテインキナーゼOsCIPK14/15の機能解析2010

    • Author(s)
      来須孝光
    • Organizer
      イネ遺伝学・分子生物学ワークショップ2010
    • Place of Presentation
      つくば国際会議場(茨城)
    • Year and Date
      2010-07-02
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 細胞内物流システムを介した植物免疫の新規制御機構、~植物免疫増強と抗菌能を併せ持つ防疫剤の創出に向けて~2010

    • Author(s)
      来須孝光
    • Organizer
      JST Innovation Bridge東京理科大学研究シーズ発表会
    • Place of Presentation
      秋葉原ダイビル(東京)
    • Year and Date
      2010-03-16
    • Related Report
      2010 Final Research Report
  • [Presentation] 細胞内物流システムを介した植物免疫の新規制御機構~植物免疫増強と抗菌能を併せ持つ防疫剤の創出に向けて~2010

    • Author(s)
      来須孝光
    • Organizer
      JST Innovation Bridge東京理科大学研究シーズ発表会
    • Place of Presentation
      秋葉原ダイビル(東京)
    • Year and Date
      2010-03-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] 植物免疫の新規制御機構~植物免疫賦活効果と抗菌活性を併せ持つ防疫剤の創出を目指して~2009

    • Author(s)
      来須孝光
    • Organizer
      東京理科大学SCITEC CLUBセミナー
    • Place of Presentation
      森戸記念館(東京)
    • Year and Date
      2009-11-13
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] DYNAMICS OF AUTOPHAGY DURING PATHOGENIC SIGNAL- TRIGGERED IMMUNE RESPONSES IN TOBACCO BY-2 CELLS2009

    • Author(s)
      来須孝光
    • Organizer
      International Symposium on Autophagy
    • Place of Presentation
      大津プリンスホテル(滋賀)
    • Year and Date
      2009-09-26
    • Related Report
      2010 Final Research Report
  • [Presentation] DYNAMICS OF AUTOPHAGY DURING PATHOGENIC SIGNAL-TRIGGERED IMMUNE RESPONSES IN TOBACCO BY-2 CELLS2009

    • Author(s)
      来須孝光
    • Organizer
      International Symposium on Autophagy
    • Place of Presentation
      大津プリンスホテル(滋賀)
    • Year and Date
      2009-09-26
    • Related Report
      2009 Annual Research Report
  • [Book] In : QUANTUM BIO-INFORMATICS IV From Quantum Information to Bio-Informatics.(Edited by Accardi, L., Freudenberg, W., Ohya, M.)2011

    • Author(s)
      来須孝光、朽津和幸、World Scientific.
    • Publisher
      Signaling network of environmental sensing and adaptation in plants: key roles of calcium ion.
    • Related Report
      2010 Final Research Report
  • [Book] Signaling network of environmental sensing and adaptation in plants : key roles of calcium ion.In : QUANTUM BIO-INFORMATICS IV From Quantum Information to Bio-Informatics.(Edited by Accardi, L., Freudenberg, W, Ohya, M.)2011

    • Author(s)
      来須孝光
    • Publisher
      World Scientific
    • Related Report
      2010 Annual Research Report
  • [Book] 植物のシグナル伝達-分子と応答-「植物の防御応答におけるカルシウムシグナリング」2010

    • Author(s)
      濱田晴康、来須孝光、朽津和幸
    • Publisher
      共立出版
    • Related Report
      2010 Final Research Report
  • [Book] 植物のシグナル伝達-分子と応答-(植物の防御応答におけるカルシウムシグナリング)2010

    • Author(s)
      濱田晴康
    • Publisher
      共立出版
    • Related Report
      2010 Annual Research Report
  • [Remarks] ホームページ等

    • URL

      http://www.tus.ac.jp/tlo/new/pdf/100607.pdf

    • Related Report
      2010 Final Research Report
  • [Remarks]

    • URL

      http://www.tus.ac.jp/tlo/new/pdf/100607.pdf

    • Related Report
      2010 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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