Elucidation of antimicrobial activity of Chinese chive against Helicobacter pylori

• Project/Area Number: 21780128
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Food science
• Research Institution: Kochi University
• Principal Investigator: SHIMAMURA Tomoko 高知大学, 教育研究部・総合科学系, 准教授 (50350179)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥5,245,123 (Direct Cost: ¥4,034,710、Indirect Cost: ¥1,210,413); Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2010: ¥695,123 (Direct Cost: ¥534,710、Indirect Cost: ¥160,413); Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
• Keywords: 農産物 / 食品機能 / 抗菌活性 / ピロリ菌 / ニラ / 食品

Research Abstract

In this study, we tried to elucidate the antimicrobial activity of Chinese chive(Allium tuberosum) against Helicobacter pylori. As a result, the extract of Chinese chive showed the growth inhibitory effect against all of the 51 H. pylori strains. In addition, it had the bactericidal activity. It was also showed that the volatile compounds in the extract of Chinese chive contributed to the antimicrobial activity against H. pylori. In particular, S-methyl methanethiosulfinate derived from methiin was the main active component.

Research Products

• [Journal Article] In vitro anti-Helicobacter pylori activity of Chinese chive(Allium tuberosum) (2011)
  • Author(s): Hayato Kudo, Hiroaki Takeuchi, Tomoko Shimamura, Youshu Kadota, Tetsuro Sugiura, Hiroyuki Ukeda
  • Journal Title: Food Science and Technology Research Volume: Vol.17 Pages: 505-513
  • NAID: 10030897352
  • Peer Reviewed
• [Journal Article] In Vitro Anti-Helicobacter pylori Activity of Chinese Chive (Allium tuberosum) (2011)
  • Author(s): H.Kudo, H.Takeuchi, et al
  • Journal Title: Food Science and Technology Research Volume: 17 Issue: 6 Pages: 505-513
  • DOI: 10.3136/fstr.17.505
  • NAID: 10030897352
  • ISSN: 1344-6606, 1881-3984
  • Peer Reviewed
• [Presentation] ニラに含まれる抗ピロリ菌関与成分の探究 (2011)
  • Author(s): 工藤勇人, 他
  • Organizer: 日本農芸化学会2011年度大会
  • Place of Presentation: (大会講演要旨集を2011年3月5日付けで発行し、本大会での発表は成立)
  • Year and Date: 2011-03-05
• [Presentation] ニラ由来抗菌性物質の抗Helicobacter pylori活性 (2011)
  • Author(s): 工藤勇人,竹内啓晃,杉浦哲朗,島村智子,受田浩之
  • Organizer: 第58回日本臨床検査医学会学術集会
  • Place of Presentation: 岡山
• [Presentation] Anti-Helicobacter pylori activity of Chinese chive(Allium tuberosum) (2011)
  • Author(s): H. Kudo, H. Takeuchi, T. Shimamura, T. Kashiwagi, T. Sugiura, H. Ukeda
  • Organizer: 111th General Meeting of the American Society for Microbiology
  • Place of Presentation: New Orleans, LA
• [Presentation] ニラに含まれる抗ピロリ菌関与成分の探究 (2011)
  • Author(s): 工藤勇人,原暢宏,竹内啓晃,島村智子,柏木丈拡,杉浦哲朗,受田浩之
  • Organizer: 日本農芸化学会2011年度大会
  • Place of Presentation: 京都
• [Presentation] Anti-Helicobacter pylori activity of Chinese chive (Allium tuberosum) (2011)
  • Author(s): H.Kudo, et al
  • Organizer: 111th General Meeting of the American Society for Microbiology
  • Place of Presentation: New Orleans, LA, USA(招待講演)
• [Presentation] ニラ由来抗菌性物質の抗Helicobacter pylori活性 (2011)
  • Author(s): 工藤勇人, 他
  • Organizer: 第58回日本臨床検査医学会学術集会
  • Place of Presentation: 岡山,岡山コンベンションセンター(招待講演)
• [Book] Current Research in Agriculture and Food Chemistry (2012)
  • Author(s): Hiroaki Takeuchi, Tomoko Shimamura, Hayato Kudo, Hiroyuki Ukeda, and Tetsuro Sugiura
  • Publisher: Research Media, Antimicrobial Activity of Natural Products and Food Components
• [Book] Current Research in Agriculture and Food Chemistry (2012)
  • Author(s): Hiroaki Takeuchi, et al
  • Publisher: Research Media